Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CDK5 | Q00535 | 2/20 | 0.41 |
| ▸ | CDK5R1 | Q15078 | 2/20 | 0.41 |
| ▸ | ITK | Q08881 | 2/20 | 0.41 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.40 |
| ▸ | NOS3 | P29474 | 1/20 | 0.39 |
| ▸ | NOS1 | P29475 | 1/20 | 0.39 |
| ▸ | NOS2 | P35228 | 1/20 | 0.39 |
| ▸ | CHEK1 | O14757 | 2/20 | 0.39 |
| ▸ | PIN1 | Q13526 | 1/20 | 0.39 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.38 |
| ▸ | TDP2 | O95551 | 3/20 | 0.37 |
| ▸ | DAO | P14920 | 1/20 | 0.37 |
| ▸ | DDO | Q99489 | 1/20 | 0.37 |
| ▸ | IMPDH2 | P12268 | 1/20 | 0.36 |
| ▸ | IMPDH1 | P20839 | 1/20 | 0.36 |
| ▸ | AR | P10275 | 1/20 | 0.36 |
| ▸ | CXCR2 | P25025 | 1/20 | 0.36 |
| ▸ | FASN | P49327 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11616817 | 0.84 | ITK (0.41) | CDK5CDK5R1ITKNOS3NOS1 | |
| SCHEMBL3735039 | 0.78 | DAO (0.58) | CDK5DAO | |
| SCHEMBL3735366 | 0.76 | KDR (0.56) | CDK5CDK5R1CHEK1DAODDO | |
| SCHEMBL3396789 | 0.76 | DAO (0.63) | NOS3NOS1NOS2PIN1DAO | |
| SCHEMBL11058812 | 0.75 | MEN1 (0.44) | CDK5CDK5R1DAODDO | |
| SCHEMBL1080585 | 0.70 | NOS3 (0.51) | ITKNOS3NOS1NOS2PIN1 | |
| SCHEMBL11056894 | 0.70 | DAO (0.58) | CDK5CDK5R1CYP19A1DAO | |
| SCHEMBL10671177 | 0.69 | CYP19A1 (0.61) | CDK5CDK5R1ITKCYP19A1IMPDH2 | |
| SCHEMBL29651657 | 0.69 | CYP19A1 (0.61) | CDK5CDK5R1ITKCYP19A1IMPDH2 | |
| SCHEMBL327599 | 0.67 | PIN1 (0.55) | NOS3NOS1NOS2PIN1DAO |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4474774-A | Acridone substituted phosphorus compounds, compositions containing same and insecticidal method of use | VELSICOL CHEMICAL CORPORATION (US) | 1984-10-02 | — | — | US | disclosed |