Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 1/20 | 0.55 |
| ▸ | TGM2 | P21980 | 1/20 | 0.53 |
| ▸ | CTSL | P07711 | 1/20 | 0.53 |
| ▸ | CTSB | P07858 | 1/20 | 0.53 |
| ▸ | CTSS | P25774 | 1/20 | 0.53 |
| ▸ | ANPEP | P15144 | 1/20 | 0.53 |
| ▸ | CPB1 | P15086 | 1/20 | 0.52 |
| ▸ | CPB2 | Q96IY4 | 1/20 | 0.52 |
| ▸ | DPP8 | Q6V1X1 | 1/20 | 0.52 |
| ▸ | DPP7 | Q9UHL4 | 1/20 | 0.52 |
| ▸ | LMNA | P02545 | 2/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.51 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.51 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.51 |
| ▸ | MEN1 | O00255 | 1/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.51 |
| ▸ | SLC1A3 | P43003 | 1/20 | 0.50 |
| ▸ | SLC1A1 | P43005 | 1/20 | 0.50 |
| ▸ | CAPN1 | P07384 | 1/20 | 0.50 |
| ▸ | CAPN2 | P17655 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11071402 | 0.89 | HTT (0.59) | HTTTGM2ANPEPCPB1CPB2 | |
| SCHEMBL10448521 | 0.84 | MEN1 (0.49) | CTSLCTSBCTSSLMNAMEN1 | |
| SCHEMBL2449575 | 0.82 | CTSL (0.77) | CTSLCTSBCTSSLMNAMEN1 | |
| SCHEMBL10414351 | 0.82 | SLC1A3 (0.57) | HTTTGM2ANPEPCPB1CPB2 | |
| SCHEMBL29472203 | 0.81 | CYP1A2 (0.53) | CTSLCTSBCTSSLMNAMEN1 | |
| SCHEMBL24845248 | 0.81 | DPP8 (0.63) | HTTTGM2ANPEPCPB1CPB2 | |
| SCHEMBL15177629 | 0.81 | DPP8 (0.63) | HTTTGM2ANPEPCPB1CPB2 | |
| SCHEMBL11061792 | 0.81 | TGM2 (0.56) | HTTTGM2ANPEPCPB1CPB2 | |
| SCHEMBL2445913 | 0.81 | CTSL (0.75) | CTSLCTSBCTSSLMNAMEN1 | |
| SCHEMBL2442047 | 0.81 | CTSL (0.75) | CTSLCTSBCTSSLMNAMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4474800-A | PROTEASE INHIBITORS, MUSCULAR DYSTROPHY | TAISHO PHARMACEUTICAL CO., LTD. (JP) | 1984-10-02 | — | — | US | disclosed |