Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA1 | P00915 | 1/20 | 0.53 |
| ▸ | CA2 | P00918 | 1/20 | 0.53 |
| ▸ | PRKCZ | Q05513 | 6/20 | 0.52 |
| ▸ | MEN1 | O00255 | 3/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.51 |
| ▸ | CNR1 | P21554 | 4/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.50 |
| ▸ | LMNA | P02545 | 1/20 | 0.50 |
| ▸ | ATM | Q13315 | 1/20 | 0.47 |
| ▸ | CNR2 | P34972 | 1/20 | 0.47 |
| ▸ | PDE5A | O76074 | 1/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.45 |
| ▸ | EGFR | P00533 | 1/20 | 0.44 |
| ▸ | ERBB2 | P04626 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11057272 | 0.94 | MEN1 (0.53) | CA1CA2PRKCZMEN1KMT2A | |
| SCHEMBL11054632 | 0.93 | PRKCZ (0.52) | CA1CA2PRKCZMEN1KMT2A | |
| SCHEMBL11064855 | 0.90 | MEN1 (0.54) | CA1CA2PRKCZMEN1KMT2A | |
| SCHEMBL11064878 | 0.86 | MEN1 (0.54) | CA1CA2PRKCZMEN1KMT2A | |
| SCHEMBL11057742 | 0.81 | ABL1 (0.49) | CA1CA2PRKCZMEN1KMT2A | |
| SCHEMBL11058366 | 0.81 | PRKCZ (0.48) | PRKCZMEN1KMT2AATMPDE5A | |
| SCHEMBL11063665 | 0.78 | MEN1 (0.49) | CA1CA2PRKCZMEN1KMT2A | |
| SCHEMBL908494 | 0.78 | CA1 (0.56) | CA1CA2PRKCZMEN1KMT2A | |
| SCHEMBL1023193 | 0.77 | CNR1 (0.58) | CA1CA2PRKCZMEN1KMT2A | |
| Hydrochloric Acid SCHEMBL1039418 | 0.76 | CNR1 (0.57) | CA1CA2PRKCZMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4447442-A | ANTIINFLAMMATORY, ANTIARTHRITIC, ANTIHISTAMINE, ANTIALLERGENS, ANALGESICS, BACTERICIDES, AND FUNGICIDES | AMERICAN CYANAMID COMPANY (US) | 1984-05-08 | — | — | US | claimed |
| US-4447442-A | ANTIINFLAMMATORY, ANTIARTHRITIC, ANTIHISTAMINE, ANTIALLERGENS, ANALGESICS, BACTERICIDES, AND FUNGICIDES | AMERICAN CYANAMID COMPANY (US) | 1984-05-08 | — | — | US | disclosed |
| EP-0070376-A1 | Heterocyclic substituted-amino-pyrazolines | AMERICAN CYANAMID COMPANY (US) | 1983-01-26 | — | — | EP | disclosed |
| US-4348527-A | ANALGESICS, BACTERICIDES, FUNGICIDES | AMERICAN CYANAMID COMPANY (US) | 1982-09-07 | — | — | US | disclosed |