Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRKCZ | Q05513 | 14/20 | 0.48 |
| ▸ | PDE5A | O76074 | 1/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | ATM | Q13315 | 1/20 | 0.42 |
| ▸ | EGFR | P00533 | 1/20 | 0.41 |
| ▸ | ERBB2 | P04626 | 1/20 | 0.41 |
| ▸ | BCHE | P06276 | 1/20 | 0.41 |
| ▸ | ACHE | P22303 | 1/20 | 0.41 |
| ▸ | MGAM | O43451 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | SI | P14410 | 1/20 | 0.41 |
| ▸ | MGAM2 | Q2M2H8 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11057272 | 0.86 | MEN1 (0.53) | PRKCZPDE5AMEN1KMT2AATM | |
| SCHEMBL11054632 | 0.85 | PRKCZ (0.52) | PRKCZPDE5AMEN1KMT2AATM | |
| SCHEMBL11057378 | 0.84 | MEN1 (0.56) | PRKCZPDE5AMEN1KMT2AATM | |
| SCHEMBL11061548 | 0.81 | CA1 (0.53) | PRKCZPDE5AMEN1KMT2AATM | |
| SCHEMBL11068397 | 0.80 | PRKCZ (0.52) | PRKCZPDE5AEGFRERBB2 | |
| SCHEMBL11064855 | 0.76 | MEN1 (0.54) | PRKCZPDE5AMEN1KMT2AATM | |
| SCHEMBL11064878 | 0.76 | MEN1 (0.54) | PRKCZPDE5AMEN1KMT2AATM | |
| SCHEMBL11057742 | 0.71 | ABL1 (0.49) | PRKCZPDE5AMEN1KMT2AATM | |
| SCHEMBL11057626 | 0.70 | MEN1 (0.55) | PRKCZPDE5AMEN1KMT2AATM | |
| SCHEMBL10690743 | 0.68 | TSHR (0.51) | MEN1KMT2ABCHEACHEMGAM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4447442-A | ANTIINFLAMMATORY, ANTIARTHRITIC, ANTIHISTAMINE, ANTIALLERGENS, ANALGESICS, BACTERICIDES, AND FUNGICIDES | AMERICAN CYANAMID COMPANY (US) | 1984-05-08 | — | — | US | claimed |
| US-4447442-A | ANTIINFLAMMATORY, ANTIARTHRITIC, ANTIHISTAMINE, ANTIALLERGENS, ANALGESICS, BACTERICIDES, AND FUNGICIDES | AMERICAN CYANAMID COMPANY (US) | 1984-05-08 | — | — | US | disclosed |
| EP-0070376-A1 | Heterocyclic substituted-amino-pyrazolines | AMERICAN CYANAMID COMPANY (US) | 1983-01-26 | — | — | EP | disclosed |
| US-4348527-A | ANALGESICS, BACTERICIDES, FUNGICIDES | AMERICAN CYANAMID COMPANY (US) | 1982-09-07 | — | — | US | disclosed |