Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ABL1 | P00519 | 2/20 | 0.49 |
| ▸ | PRKCZ | Q05513 | 9/20 | 0.39 |
| ▸ | PDE5A | O76074 | 2/20 | 0.39 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.36 |
| ▸ | CNR1 | P21554 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | ATM | Q13315 | 1/20 | 0.36 |
| ▸ | BRD4 | O60885 | 1/20 | 0.35 |
| ▸ | CA1 | P00915 | 1/20 | 0.35 |
| ▸ | CA2 | P00918 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11054632 | 0.85 | PRKCZ (0.52) | PRKCZPDE5APTGS2MEN1KMT2A | |
| SCHEMBL11092462 | 0.83 | ABL1 (0.49) | ABL1PRKCZPDE5APTGS2ALDH1A1 | |
| SCHEMBL11061548 | 0.81 | CA1 (0.53) | PRKCZPDE5ACNR1ALDH1A1LMNA | |
| SCHEMBL11061067 | 0.80 | ABL1 (0.74) | ABL1PRKCZPDE5AALDH1A1LMNA | |
| SCHEMBL11095686 | 0.79 | ABL1 (0.46) | ABL1PRKCZPDE5AALDH1A1LMNA | |
| SCHEMBL11057272 | 0.78 | MEN1 (0.53) | PRKCZPDE5ACNR1ALDH1A1LMNA | |
| SCHEMBL11093164 | 0.78 | ABL1 (0.45) | ABL1PRKCZPDE5ACNR1BRD4 | |
| SCHEMBL11061324 | 0.76 | ABL1 (0.55) | ABL1PRKCZPDE5AALDH1A1LMNA | |
| SCHEMBL11091186 | 0.75 | ABL1 (0.43) | ABL1PRKCZPDE5ACNR1ALDH1A1 | |
| SCHEMBL907974 | 0.73 | PRKCZ (0.41) | ABL1PRKCZPDE5APTGS2BRD4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4447442-A | ANTIINFLAMMATORY, ANTIARTHRITIC, ANTIHISTAMINE, ANTIALLERGENS, ANALGESICS, BACTERICIDES, AND FUNGICIDES | AMERICAN CYANAMID COMPANY (US) | 1984-05-08 | — | — | US | claimed |
| US-4448973-A | ANTIINFLAMMATORY, ANALGESIC AGENTS; BACTERICIDES, FUNGICIDES | AMERICAN CYANAMID COMPANY (US) | 1984-05-15 | — | — | US | disclosed |
| US-4447442-A | ANTIINFLAMMATORY, ANTIARTHRITIC, ANTIHISTAMINE, ANTIALLERGENS, ANALGESICS, BACTERICIDES, AND FUNGICIDES | AMERICAN CYANAMID COMPANY (US) | 1984-05-08 | — | — | US | disclosed |
| EP-0070376-A1 | Heterocyclic substituted-amino-pyrazolines | AMERICAN CYANAMID COMPANY (US) | 1983-01-26 | — | — | EP | disclosed |
| US-4348527-A | ANALGESICS, BACTERICIDES, FUNGICIDES | AMERICAN CYANAMID COMPANY (US) | 1982-09-07 | — | — | US | disclosed |