SCHEMBL11061550

SCHEMBL11061550

CCCCCC1CCC(CCc2ccc(-c3ccc(CCC)cc3)cc2)CC1

nearest known ligand 0.49

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAOA P21397 1/20 0.49
MAOB P27338 1/20 0.49
HRH3 Q9Y5N1 3/20 0.42
RARB P10826 6/20 0.41
TSHR P16473 1/20 0.41
HSD17B10 Q99714 1/20 0.41
MAPT P10636 2/20 0.41
MEN1 O00255 2/20 0.41
KMT2A Q03164 2/20 0.41
ALDH1A1 P00352 1/20 0.41
RARA P10276 1/20 0.41
MTOR P42345 1/20 0.41
GPR84 Q9NQS5 1/20 0.40
SPHK1 Q9NYA1 1/20 0.39
NPC1 O15118 1/20 0.39
RAB9A P51151 1/20 0.39
GAA P10253 1/20 0.39
HRH4 Q9H3N8 1/20 0.39
CYP3A4 P08684 1/20 0.38
CYP2C8 P10632 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11061549 1.00 MAOA (0.49) MAOAMAOBHRH3RARBTSHR
SCHEMBL10789703 0.97 MAOA (0.44) MAOAMAOBHRH3RARBTSHR
SCHEMBL10789712 0.97 MAOA (0.44) MAOAMAOBHRH3RARBTSHR
SCHEMBL10902212 0.95 GPR84 (0.44) MAOAMAOBHRH3RARBTSHR
SCHEMBL10902205 0.95 GPR84 (0.44) MAOAMAOBHRH3RARBTSHR
SCHEMBL11062059 0.95 MAOA (0.53) MAOAMAOBHRH3HSD17B10MEN1
SCHEMBL11062065 0.95 MAOA (0.53) MAOAMAOBHRH3HSD17B10MEN1
SCHEMBL11058295 0.93 HRH3 (0.49) HRH3RARBTSHRHSD17B10MAPT
SCHEMBL11058303 0.93 HRH3 (0.49) HRH3RARBTSHRHSD17B10MAPT
SCHEMBL10903184 0.93 MAOA (0.42) MAOAMAOBHRH3RARBTSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4439015-A Disubstituted ethanes HOFFMANN-LA ROCHE INC. (US) 1984-03-27 US disclosed