Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LPAR3 | Q9UBY5 | 3/20 | 0.34 |
| ▸ | LPAR1 | Q92633 | 2/20 | 0.34 |
| ▸ | LPAR2 | Q9HBW0 | 2/20 | 0.34 |
| ▸ | FBP1 | P09467 | 1/20 | 0.33 |
| ▸ | TPI1 | P60174 | 2/20 | 0.31 |
| ▸ | S1PR1 | P21453 | 4/20 | 0.31 |
| ▸ | S1PR3 | Q99500 | 4/20 | 0.31 |
| ▸ | PGK1 | P00558 | 1/20 | 0.30 |
| ▸ | PGK2 | P07205 | 1/20 | 0.30 |
| ▸ | S1PR4 | O95977 | 2/20 | 0.30 |
| ▸ | S1PR5 | Q9H228 | 2/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8084387 | 0.82 | LPAR3 (0.34) | LPAR3LPAR1LPAR2FBP1TPI1 | |
| SCHEMBL7045722 | 0.81 | ALDH1A1 (0.40) | — | |
| SCHEMBL14582611 | 0.81 | LPAR3 (0.41) | LPAR3LPAR1LPAR2FBP1TPI1 | |
| SCHEMBL6260932 | 0.79 | S1PR1 (0.38) | LPAR3LPAR1LPAR2FBP1TPI1 | |
| SCHEMBL23633124 | 0.76 | FBP1 (0.35) | LPAR3LPAR1LPAR2FBP1TPI1 | |
| SCHEMBL29106448 | 0.76 | LPAR3 (0.37) | LPAR3LPAR1LPAR2FBP1TPI1 | |
| SCHEMBL11061589 | 0.76 | FBP1 (0.35) | LPAR3LPAR1LPAR2FBP1TPI1 | |
| SCHEMBL5974079 | 0.75 | LPAR3 (0.39) | LPAR3LPAR1LPAR2FBP1TPI1 | |
| SCHEMBL2470417 | 0.75 | LPAR3 (0.39) | LPAR3LPAR1LPAR2FBP1TPI1 | |
| Phosphoric Acid SCHEMBL17477137 | 0.73 | LPAR3 (0.38) | LPAR3LPAR1LPAR2FBP1TPI1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4424172-A | 5,5-Bis-(Bromomethyl)-2-hydroxy-2-oxo-1,3,2-dioxaphosphorinanes and process for preparing same | BORG-WARNER CHEMICALS, INC. (US) | 1984-01-03 | — | — | US | disclosed |
| US-4361664-A | 5,5-BIS(BROMOMETHYL)-2-HYDROXY-2-OXO-1,3,2-DIOXAPHOSPHORINANE | BORG-WARNER CHEMICALS, INC. (US) | 1982-11-30 | — | — | US | disclosed |