Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARA | Q07869 | 2/20 | 0.44 |
| ▸ | MAOB | P27338 | 1/20 | 0.43 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.42 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | HTR2A | P28223 | 1/20 | 0.42 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.40 |
| ▸ | NOS3 | P29474 | 1/20 | 0.39 |
| ▸ | NOS1 | P29475 | 1/20 | 0.39 |
| ▸ | NOS2 | P35228 | 1/20 | 0.39 |
| ▸ | ABCC1 | P33527 | 1/20 | 0.39 |
| ▸ | PTPN2 | P17706 | 1/20 | 0.39 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.39 |
| ▸ | PPARG | P37231 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11063245 | 0.80 | SMN1; SMN2 (0.43) | PPARAMAOBCYP1A2ABCB11CYP3A4 | |
| SCHEMBL9796952 | 0.77 | GAA (0.36) | CYP1A2HSD11B1ALDH1A1KMT2A | |
| SCHEMBL9796959 | 0.77 | GAA (0.36) | CYP1A2HSD11B1ALDH1A1KMT2A | |
| SCHEMBL16859612 | 0.75 | NOS3 (0.45) | MAOBPTGS2CYP1A2KDM4EMAPT | |
| SCHEMBL16865353 | 0.75 | NOS3 (0.45) | MAOBPTGS2CYP1A2KDM4EMAPT | |
| SCHEMBL16865329 | 0.75 | NOS3 (0.45) | MAOBPTGS2CYP1A2KDM4EMAPT | |
| SCHEMBL11062659 | 0.74 | L3MBTL1 (0.45) | PPARACYP1A2ABCB11CYP3A4TSHR | |
| SCHEMBL11062480 | 0.73 | ABCB11 (0.41) | PPARACYP1A2ABCB11CYP3A4TSHR | |
| SCHEMBL31376546 | 0.72 | MAOB (0.44) | PPARAMAOBPTGS2CYP1A2ABCB11 | |
| SCHEMBL11319754 | 0.72 | NOS3 (0.45) | MAOBPTGS2CYP1A2KDM4EMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4425282-A | Preparation of 3-(arylvinyl)-2,2-dimethyl-cyclopropane-1-carboxylic acid esters and new intermediate therefor | BAYER AKTIENGESELLSCHAFT (DE) | 1984-01-10 | — | — | US | disclosed |
| EP-0018533-B1 | SUBSTITUTED PENTANE (OR PENTENE) CARBOXYLIC ACIDS AND THEIR DERIVATIVES, PROCESS FOR THEIR PREPARATION AND THEIR USE FOR THE PREPARATION OF 3-(ARYLVINYL)-2,2-DIMETHYL-CYCLOPROPANE-1-CARBOXYLATES | BAYER AG (DE) | 1983-01-26 | — | — | EP | disclosed |
| EP-0018533-A1 | Substituted pentane (or pentene) carboxylic acids and their derivatives, process for their preparation and their use for the preparation of 3-(arylvinyl)-2,2-dimethyl-cyclopropane-1-carboxylates | BAYER AG (DE) | 1980-11-12 | — | — | EP | disclosed |