Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SCN5A | Q14524 | 1/20 | 0.43 |
| ▸ | ESR1 | P03372 | 7/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | GAA | P10253 | 2/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | GLA | P06280 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | ESR2 | Q92731 | 4/20 | 0.39 |
| ▸ | AR | P10275 | 2/20 | 0.39 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.37 |
| ▸ | ATM | Q13315 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | NQO1 | P15559 | 1/20 | 0.36 |
| ▸ | LTA4H | P09960 | 1/20 | 0.35 |
| ▸ | CA12 | O43570 | 2/20 | 0.35 |
| ▸ | CA1 | P00915 | 2/20 | 0.35 |
| ▸ | CA2 | P00918 | 2/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18152141 | 0.87 | SCN5A (0.46) | SCN5AESR1ALDH1A1GAAKDM4E | |
| SCHEMBL6985548 | 0.82 | NQO1 (0.42) | SCN5AALDH1A1GAAKDM4EGLA | |
| SCHEMBL11131743 | 0.82 | NQO1 (0.46) | ESR1ALDH1A1GAAKDM4EGLA | |
| SCHEMBL8940830 | 0.80 | ESR1 (0.42) | SCN5AESR1ALDH1A1GAAKDM4E | |
| SCHEMBL11215025 | 0.78 | ALDH1A1 (0.40) | SCN5AESR1ALDH1A1GAAKDM4E | |
| SCHEMBL23361704 | 0.77 | ALDH1A1 (0.49) | ESR1ALDH1A1GAAKDM4EMAPT | |
| SCHEMBL17644154 | 0.76 | HSD17B10 (0.42) | ALDH1A1GAAKDM4EMAPTHPGD | |
| SCHEMBL10460608 | 0.76 | MAOA (0.43) | SCN5AESR1ESR2TRPA1ATM | |
| SCHEMBL8072909 | 0.75 | ALDH1A1 (0.49) | SCN5AESR1ALDH1A1GAAKDM4E | |
| SCHEMBL2117233 | 0.75 | NQO1 (0.36) | ALDH1A1GAAKDM4EGLAMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4438284-A | Catalysts for oxidative coupling of phenols | THE DOW CHEMICAL COMPANY (US) | 1984-03-20 | — | — | US | disclosed |
| US-4354048-A | Copper chromite catalysts for oxidative coupling of phenols | THE DOW CHEMICAL COMPANY (US) | 1982-10-12 | — | — | US | disclosed |
| US-4354047-A | Nickel catalysts for oxidative coupling of phenols | THE DOW CHEMICAL COMPANY (US) | 1982-10-12 | — | — | US | disclosed |