Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 6/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 5/20 | 0.40 |
| ▸ | CASP1 | P29466 | 5/20 | 0.40 |
| ▸ | CASP7 | P55210 | 5/20 | 0.40 |
| ▸ | GLA | P06280 | 2/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | CSNK1E | P49674 | 2/20 | 0.38 |
| ▸ | ADORA2A | P29274 | 2/20 | 0.38 |
| ▸ | ADORA1 | P30542 | 2/20 | 0.38 |
| ▸ | MAPK14 | Q16539 | 2/20 | 0.36 |
| ▸ | HIF1A | Q16665 | 4/20 | 0.36 |
| ▸ | USP2 | O75604 | 4/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 3/20 | 0.36 |
| ▸ | CYP2D6 | P10635 | 3/20 | 0.36 |
| ▸ | MEN1 | O00255 | 2/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | TSHR | P16473 | 2/20 | 0.36 |
| ▸ | HPGD | P15428 | 2/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11062613 | 0.85 | ALDH1A1 (0.40) | ALDH1A1HSD17B10CYP1A2CASP1CASP7 | |
| SCHEMBL11074426 | 0.77 | MAPK14 (0.44) | ALDH1A1CSNK1EADORA2AADORA1MAPK14 | |
| SCHEMBL1786845 | 0.65 | NPSR1 (0.56) | ALDH1A1CYP1A2ADORA2AADORA1CYP2C9 | |
| SCHEMBL14067727 | 0.60 | MAPK14 (0.47) | ALDH1A1ADORA2AADORA1MAPK14 | |
| SCHEMBL28746869 | 0.60 | MAPK14 (0.61) | CSNK1EADORA2AADORA1MAPK14ADORA3 | |
| SCHEMBL1302241 | 0.59 | KDM4E (0.39) | GLAKMT2ACYP3A4 | |
| SCHEMBL11068704 | 0.58 | MAPK14 (0.47) | ALDH1A1MAPK14 | |
| SCHEMBL8502939 | 0.57 | MEN1 (0.47) | ADORA2AADORA1MAPK14MEN1KMT2A | |
| SCHEMBL19992642 | 0.56 | CYP1A2 (0.54) | CYP1A2LMNAMAPK14CYP2D6MEN1 | |
| SCHEMBL10368512 | 0.55 | ALDH1A1 (0.51) | ALDH1A1HSD17B10CYP1A2CASP1CASP7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0044696-B1 | 5-OXO-2,5,-DIHYDRO-1,2,4-TRIAZINES, METHODS FOR THEIR PRODUCTION, HERBICIDAL COMPOSITIONS COMPRISING THEM, AND THEIR USE AS HERBICIDES | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1984-10-17 | — | — | EP | disclosed |
| US-4451283-A | HERBICIDES | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1984-05-29 | — | — | US | disclosed |
| EP-0044696-A2 | 5-Oxo-2,5,-dihydro-1,2,4-triazines, methods for their production, herbicidal compositions comprising them, and their use as herbicides | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1982-01-27 | — | — | EP | disclosed |