Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK14 | Q16539 | 13/20 | 0.44 |
| ▸ | MAPK13 | O15264 | 11/20 | 0.44 |
| ▸ | MAPK12 | P53778 | 11/20 | 0.44 |
| ▸ | MAPK11 | Q15759 | 11/20 | 0.44 |
| ▸ | ADORA2A | P29274 | 2/20 | 0.38 |
| ▸ | ADORA1 | P30542 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.37 |
| ▸ | CCNA2 | P20248 | 1/20 | 0.36 |
| ▸ | CDK2 | P24941 | 1/20 | 0.36 |
| ▸ | CSNK1E | P49674 | 1/20 | 0.36 |
| ▸ | CDK5 | Q00535 | 1/20 | 0.36 |
| ▸ | CDK5R1 | Q15078 | 1/20 | 0.36 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.36 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.36 |
| ▸ | GCGR | P47871 | 2/20 | 0.35 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11062596 | 0.77 | ALDH1A1 (0.40) | MAPK14ADORA2AADORA1ALDH1A1CSNK1E | |
| SCHEMBL11069470 | 0.70 | LIPE (0.42) | ALDH1A1L3MBTL1 | |
| SCHEMBL11068704 | 0.67 | MAPK14 (0.47) | MAPK14MAPK13MAPK12MAPK11ALDH1A1 | |
| SCHEMBL11218346 | 0.65 | KMT2A (0.47) | ADORA1ALDH1A1L3MBTL1ADORA3 | |
| SCHEMBL1786845 | 0.65 | NPSR1 (0.56) | ADORA2AADORA1ALDH1A1L3MBTL1ADORA3 | |
| SCHEMBL17541749 | 0.64 | KDM4C (0.48) | MAPK14MAPK13MAPK12MAPK11ALDH1A1 | |
| SCHEMBL5792669 | 0.63 | MAPK14 (0.68) | MAPK14MAPK13MAPK12MAPK11ALDH1A1 | |
| SCHEMBL11071668 | 0.60 | TDP2 (0.45) | MAPK14ALDH1A1 | |
| SCHEMBL14067727 | 0.60 | MAPK14 (0.47) | MAPK14ADORA2AADORA1ALDH1A1PTGS1 | |
| SCHEMBL28746869 | 0.60 | MAPK14 (0.61) | MAPK14MAPK13MAPK12MAPK11ADORA2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0044696-B1 | 5-OXO-2,5,-DIHYDRO-1,2,4-TRIAZINES, METHODS FOR THEIR PRODUCTION, HERBICIDAL COMPOSITIONS COMPRISING THEM, AND THEIR USE AS HERBICIDES | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1984-10-17 | — | — | EP | disclosed |
| US-4451283-A | HERBICIDES | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1984-05-29 | — | — | US | disclosed |
| EP-0044696-A2 | 5-Oxo-2,5,-dihydro-1,2,4-triazines, methods for their production, herbicidal compositions comprising them, and their use as herbicides | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1982-01-27 | — | — | EP | disclosed |