Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 9/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 8/20 | 0.40 |
| ▸ | USP2 | O75604 | 6/20 | 0.40 |
| ▸ | CASP1 | P29466 | 6/20 | 0.40 |
| ▸ | CASP7 | P55210 | 6/20 | 0.40 |
| ▸ | HIF1A | Q16665 | 6/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 5/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 5/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.36 |
| ▸ | CYP2D6 | P10635 | 4/20 | 0.36 |
| ▸ | HPGD | P15428 | 2/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.36 |
| ▸ | LMNA | P02545 | 2/20 | 0.36 |
| ▸ | GLA | P06280 | 2/20 | 0.36 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.36 |
| ▸ | ADORA2A | P29274 | 3/20 | 0.35 |
| ▸ | ADORA1 | P30542 | 3/20 | 0.35 |
| ▸ | ADORA3 | P0DMS8 | 2/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11062596 | 0.85 | ALDH1A1 (0.40) | ALDH1A1CYP1A2USP2CASP1CASP7 | |
| SCHEMBL11073774 | 0.77 | ALDH1A1 (0.47) | ALDH1A1HSD17B10KMT2AHPGDLMNA | |
| SCHEMBL11218668 | 0.68 | BRD4 (0.48) | ALDH1A1CYP1A2CASP1CASP7HIF1A | |
| SCHEMBL1789226 | 0.65 | NPSR1 (0.64) | ALDH1A1CYP1A2CYP2C9CYP2C19MEN1 | |
| SCHEMBL115647 | 0.64 | LMNA (0.47) | ALDH1A1CYP1A2USP2KMT2AMAPK1 | |
| SCHEMBL11074426 | 0.62 | MAPK14 (0.44) | ALDH1A1ADORA2AADORA1ADORA3L3MBTL1 | |
| SCHEMBL10611151 | 0.60 | NR1H4 (0.46) | ALDH1A1HSD17B10CYP2C9CYP2C19MEN1 | |
| SCHEMBL14875789 | 0.60 | GAA (0.50) | ALDH1A1CYP1A2CASP1CASP7HSD17B10 | |
| SCHEMBL22997641 | 0.58 | CYP1A2 (0.35) | ALDH1A1CYP1A2USP2CASP1CASP7 | |
| SCHEMBL5892111 | 0.58 | MAPT (0.45) | ALDH1A1HSD17B10MEN1KMT2AMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0044696-B1 | 5-OXO-2,5,-DIHYDRO-1,2,4-TRIAZINES, METHODS FOR THEIR PRODUCTION, HERBICIDAL COMPOSITIONS COMPRISING THEM, AND THEIR USE AS HERBICIDES | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1984-10-17 | — | — | EP | disclosed |
| US-4451283-A | HERBICIDES | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1984-05-29 | — | — | US | disclosed |
| EP-0044696-A2 | 5-Oxo-2,5,-dihydro-1,2,4-triazines, methods for their production, herbicidal compositions comprising them, and their use as herbicides | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1982-01-27 | — | — | EP | disclosed |