Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.52 |
| ▸ | MAPK1 | P28482 | 4/20 | 0.52 |
| ▸ | TSHR | P16473 | 2/20 | 0.52 |
| ▸ | HPGD | P15428 | 1/20 | 0.52 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.52 |
| ▸ | MAPT | P10636 | 1/20 | 0.52 |
| ▸ | PKM | P14618 | 1/20 | 0.49 |
| ▸ | GAA | P10253 | 2/20 | 0.48 |
| ▸ | LMNA | P02545 | 2/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.48 |
| ▸ | ENPP1 | P22413 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | PDE2A | O00408 | 1/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16986457 | 0.74 | IDH1 (0.38) | KDM4EALDH1A1L3MBTL1 | |
| SCHEMBL8181080 | 0.71 | ALDH1A1 (0.61) | KDM4EALDH1A1MAPK1TSHRHPGD | |
| SCHEMBL22342534 | 0.69 | KDM4E (1.00) | KDM4EALDH1A1MAPK1TSHRHPGD | |
| SCHEMBL10123160 | 0.69 | KDM4E (0.67) | KDM4EALDH1A1MAPK1TSHRHPGD | |
| SCHEMBL11062897 | 0.68 | KDM4E (0.74) | KDM4EALDH1A1MAPK1TSHRHPGD | |
| SCHEMBL709421 | 0.68 | KDM4E (0.51) | KDM4EALDH1A1MAPK1TSHRHPGD | |
| SCHEMBL5151528 | 0.66 | ALDH1A1 (0.67) | KDM4EALDH1A1MAPK1TSHRHPGD | |
| SCHEMBL609785 | 0.66 | ALDH1A1 (0.67) | KDM4EALDH1A1MAPK1TSHRHPGD | |
| SCHEMBL259453 | 0.65 | ALDH1A1 (1.00) | KDM4EALDH1A1MAPK1TSHRHPGD | |
| SCHEMBL22271284 | 0.65 | IDH1 (0.50) | KDM4EGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010087294-A1 | TRIAZOLOPYRIMIDINE DERIVATIVE OR ITS SALT, PROCESS FOR PRODUCING THE SAME AND PESTICIDE CONTAINING THE SAME | ISHIHARA SANGYO KAISHA, LTD. (JP) | 2010-08-05 | — | — | WO | disclosed |