Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IKBKB | O14920 | 1/20 | 0.48 |
| ▸ | PRKCZ | Q05513 | 3/20 | 0.46 |
| ▸ | HRH1 | P35367 | 3/20 | 0.46 |
| ▸ | ROCK1 | Q13464 | 4/20 | 0.46 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.46 |
| ▸ | PRKACA | P17612 | 1/20 | 0.46 |
| ▸ | PRKCD | Q05655 | 1/20 | 0.46 |
| ▸ | PRKG1 | Q13976 | 1/20 | 0.46 |
| ▸ | PKN1 | Q16512 | 1/20 | 0.46 |
| ▸ | PKN2 | Q16513 | 1/20 | 0.46 |
| ▸ | AAK1 | Q2M2I8 | 1/20 | 0.46 |
| ▸ | CDC42BPA | Q5VT25 | 1/20 | 0.46 |
| ▸ | Q6ZSR9 | Q6ZSR9 | 1/20 | 0.46 |
| ▸ | BMP2K | Q9NSY1 | 1/20 | 0.46 |
| ▸ | CDC42BPB | Q9Y5S2 | 1/20 | 0.46 |
| ▸ | JUND | P17535 | 1/20 | 0.46 |
| ▸ | FOSB | P53539 | 1/20 | 0.46 |
| ▸ | ACVR1B | P36896 | 1/20 | 0.44 |
| ▸ | TGFBR1 | P36897 | 1/20 | 0.44 |
| ▸ | ACVR1 | Q04771 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16865838 | 0.82 | ENPP2 (0.42) | — | |
| SCHEMBL11066031 | 0.78 | HRH1 (0.53) | HRH1JUNDFOSBTLR9TLR8 | |
| SCHEMBL5758278 | 0.78 | HTR2C (0.56) | JUNDFOSBTGFBR1ACVR1TLR9 | |
| SCHEMBL11072304 | 0.78 | HRH3 (0.50) | — | |
| SCHEMBL11063126 | 0.78 | IKBKB (0.68) | IKBKBPRKCZHRH1ROCK1ROCK2 | |
| Hydrochloric Acid SCHEMBL11071373 | 0.77 | HRH1 (0.51) | HRH1JUNDFOSBTLR9TLR8 | |
| Hydrochloric Acid SCHEMBL27302123 | 0.77 | TLR9 (0.53) | IKBKBHRH1ROCK1ROCK2PRKACA | |
| Hydrochloric Acid SCHEMBL7096368 | 0.77 | HTR2C (0.57) | JUNDFOSBTGFBR1ACVR1TLR9 | |
| SCHEMBL942733 | 0.76 | HRH1 (0.62) | IKBKBHRH1HTR2CNMT1 | |
| SCHEMBL29995290 | 0.76 | HRH1 (0.62) | IKBKBHRH1HTR2CNMT1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4443462-A | Antipsychotic 4-(naphthalenyloxy)piperidine derivatives | MERRELL DOW PHARMACEUTICALS INC. (US) | 1984-04-17 | — | — | US | disclosed |