Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IKBKB | O14920 | 1/20 | 0.68 |
| ▸ | HRH1 | P35367 | 4/20 | 0.65 |
| ▸ | SLC6A2 | P23975 | 6/20 | 0.59 |
| ▸ | SLC6A4 | P31645 | 6/20 | 0.59 |
| ▸ | KCNH2 | Q12809 | 3/20 | 0.59 |
| ▸ | HTR3A | P46098 | 2/20 | 0.59 |
| ▸ | SLC6A3 | Q01959 | 4/20 | 0.58 |
| ▸ | HTR2A | P28223 | 1/20 | 0.58 |
| ▸ | HTR2C | P28335 | 1/20 | 0.58 |
| ▸ | HTR7 | P34969 | 1/20 | 0.58 |
| ▸ | HTR2B | P41595 | 1/20 | 0.58 |
| ▸ | HTR4 | Q13639 | 1/20 | 0.58 |
| ▸ | ROCK1 | Q13464 | 4/20 | 0.56 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.56 |
| ▸ | PRKACA | P17612 | 1/20 | 0.56 |
| ▸ | PRKCD | Q05655 | 1/20 | 0.56 |
| ▸ | PRKG1 | Q13976 | 1/20 | 0.56 |
| ▸ | PKN1 | Q16512 | 1/20 | 0.56 |
| ▸ | PKN2 | Q16513 | 1/20 | 0.56 |
| ▸ | AAK1 | Q2M2I8 | 1/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL7452746 | 0.98 | IKBKB (0.66) | IKBKBHRH1SLC6A2SLC6A4KCNH2 | |
| SCHEMBL30477858 | 0.87 | CYP1A2 (0.50) | IKBKBHRH1SLC6A2SLC6A4KCNH2 | |
| SCHEMBL16902878 | 0.87 | CYP1A2 (0.50) | IKBKBHRH1SLC6A2SLC6A4KCNH2 | |
| SCHEMBL2582566 | 0.84 | IKBKB (0.51) | IKBKBHRH1SLC6A2SLC6A4KCNH2 | |
| SCHEMBL11073591 | 0.83 | IKBKB (0.60) | IKBKBHRH1SLC6A4HTR2CHTR2B | |
| SCHEMBL11073457 | 0.83 | IKBKB (0.60) | IKBKBHRH1HTR2CHTR2BROCK1 | |
| SCHEMBL23842763 | 0.81 | SLC6A4 (0.60) | IKBKBSLC6A2SLC6A4KCNH2HTR3A | |
| SCHEMBL5368065 | 0.81 | FAAH (0.50) | IKBKBSLC6A2SLC6A4KCNH2HTR3A | |
| Hydrochloric Acid SCHEMBL6964855 | 0.80 | SLC6A4 (0.58) | IKBKBSLC6A2SLC6A4KCNH2HTR3A | |
| Hydrochloric Acid SCHEMBL30690927 | 0.80 | SLC6A4 (0.58) | IKBKBSLC6A2SLC6A4KCNH2HTR3A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230150929-A1 | SELECTIVE NON-CYCLIC NUCLEOTIDE ACTIVATORS FOR THE CAMP SENSOR EPAC1 | UNIV TEXAS (US) | 2023-05-18 | — | — | US | disclosed |
| US-4443462-A | Antipsychotic 4-(naphthalenyloxy)piperidine derivatives | MERRELL DOW PHARMACEUTICALS INC. (US) | 1984-04-17 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230150929-A1 | SELECTIVE NON-CYCLIC NUCLEOTIDE ACTIVATORS FOR THE CAMP SENSOR EPAC1 | CREB1, RAPGEF4, ATF4 | IKBKB 2278/4885HRH1 2472/4885SLC6A2 4364/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.