SCHEMBL11063152

SCHEMBL11063152

CON(Cc1ccccc1)c1ccc(O)cc1C

nearest known ligand 0.42

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ERAP1 Q9NZ08 1/20 0.42
MAPT P10636 3/20 0.40
GAA P10253 2/20 0.40
KDM4E B2RXH2 1/20 0.40
ESR2 Q92731 1/20 0.40
LMNA P02545 2/20 0.39
MEN1 O00255 3/20 0.39
KMT2A Q03164 3/20 0.39
TSHR P16473 2/20 0.38
OPRM1 P35372 2/20 0.38
OPRD1 P41143 2/20 0.38
OPRK1 P41145 2/20 0.38
G6PC1 P35575 1/20 0.38
PDK1 Q15118 2/20 0.37
CYP2C19 P33261 1/20 0.37
TRPM8 Q7Z2W7 1/20 0.36
EGFR P00533 1/20 0.36
ERBB2 P04626 1/20 0.36
ALOX5 P09917 1/20 0.36
ALDH1A1 P00352 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7002879 0.81 CYP2C19 (0.49) ERAP1ESR2LMNATSHROPRM1
SCHEMBL9853509 0.69 TSHR (0.50) MAPTGAAKDM4ELMNAMEN1
SCHEMBL28015722 0.69 TSHR (0.37) MAPTGAAKDM4ELMNAMEN1
SCHEMBL28015127 0.69 NR1H2 (0.37) MAPTGAAKDM4EMEN1KMT2A
SCHEMBL28280483 0.67 CYP2C19 (0.61) LMNATSHRCYP2C19TRPM8ALDH1A1
SCHEMBL14923097 0.67 ESR2 (0.47) MAPTGAAKDM4EESR2LMNA
SCHEMBL9463538 0.67 HTR1D (0.46) LMNAKMT2ATSHRCYP2C19ALDH1A1
SCHEMBL498871 0.66 ALDH1A1 (0.51) MAPTGAAKDM4ELMNATSHR
SCHEMBL1285894 0.66 FFAR4 (0.61) MAPTLMNACYP2C19
SCHEMBL7003535 0.66 NR3C1 (0.49) GAATSHRG6PC1CYP2C19

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
JP-59167293-A None JP disclosed
JP-S59167293-A THERMAL RECORDING MATERIAL RICOH CO LTD 1984-09-20 JP disclosed