SCHEMBL7002879

SCHEMBL7002879

Cc1cc(O)ccc1N(Cc1ccccc1)Cc1ccccc1

nearest known ligand 0.49

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP2C19 P33261 1/20 0.49
NR3C1 P04150 3/20 0.48
TSHR P16473 2/20 0.46
ERAP1 Q9NZ08 1/20 0.46
ESR2 Q92731 1/20 0.44
OPRM1 P35372 2/20 0.41
OPRD1 P41143 2/20 0.41
OPRK1 P41145 2/20 0.41
EGFR P00533 2/20 0.41
ERBB2 P04626 2/20 0.41
TSPO P30536 1/20 0.41
PDK1 Q15118 1/20 0.40
CRHR1 P34998 1/20 0.40
LMNA P02545 1/20 0.40
TRPM8 Q7Z2W7 1/20 0.40
CRHBP P24387 1/20 0.40
CRHR2 Q13324 1/20 0.40
ALOX5 P09917 1/20 0.40
ALDH1A1 P00352 1/20 0.39
PGR P06401 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11063152 0.81 ERAP1 (0.42) CYP2C19TSHRERAP1ESR2OPRM1
SCHEMBL9861882 0.79 ALOX5 (0.46) CYP2C19TSHRERAP1OPRM1OPRD1
SCHEMBL3006766 0.77 TRPM8 (0.54) CYP2C19NR3C1TSHRTRPM8ALDH1A1
SCHEMBL7003535 0.77 NR3C1 (0.49) CYP2C19NR3C1TSHR
SCHEMBL14419254 0.76 NR3C1 (0.49) NR3C1TSPOTRPM8PGRNR3C2
SCHEMBL5624047 0.75 NR3C1 (0.48) NR3C1TSPOTRPM8PGRNR3C2
Hydrochloric Acid SCHEMBL6499582 0.75 ESR2 (0.61) CYP2C19TSHRESR2PDK1ALOX5
SCHEMBL22014041 0.75 CYP2C19 (0.43) CYP2C19NR3C1TSHREGFRTSPO
SCHEMBL273356 0.74 CYP2C19 (0.46) CYP2C19NR3C1TSHRTSPOCRHR1
SCHEMBL18507803 0.74 CYP2C19 (0.46) CYP2C19NR3C1TSHRTSPOCRHR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6635602-B1 Heat sensitive and pressure sensitive recording material; synthesised directly by the reaction of two derivatives of amino phenols, phthalic anhydrides, keto acids and/or diphenylamines with a phenol derivative CIBA SPECIALTY CHEMICALS CORPORATION 2003-10-21 US disclosed
US-6566302-B1 For use in heat sensitive and pressure sensitive recording materials CIBA SPECIALTY CHEMICALS CORPORATION 2003-05-20 US disclosed
EP-1107972-B1 PREPARATION PROCESS FOR MANUFACTURE AND PURIFICATION OF MIXTURES OF FLUORAN COMPOUNDS AND RECORDING MATERIAL COMPRISING SAID MIXTURES OF FLUORAN CIBA SC HOLDING AG (CH) 2003-01-02 EP disclosed
EP-1115579-B1 MONOPHASE SOLID SOLUTIONS COMPRISING A PLURALITY OF COLOUR FORMER COMPOUNDS AND PROCESS FOR THEIR PREPARATION CIBA SC HOLDING AG (CH) 2002-11-20 EP disclosed
EP-1115579-A1 MONOPHASE SOLID SOLUTIONS COMPRISING A PLURALITY OF COLOUR FORMER COMPOUNDS AND PROCESS FOR THEIR PREPARATION Ciba SC Holding AG (CH) 2001-07-18 EP disclosed
WO-2000026037-A1 HEAT SENSITIVE RECORDING MATERIAL CIBA SPECIALTY CHEMICALS HOLDING INC. (CH) 2000-05-11 WO disclosed
WO-2000012318-A1 MONOPHASE SOLID SOLUTIONS COMPRISING A PLURALITY OF COLOUR FORMER COMPOUNDS AND PROCESS FOR THEIR PREPARATION CIBA SPECIALTY CHEMICALS HOLDING INC. (CH) 2000-03-09 WO disclosed