Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KIF11 | P52732 | 2/20 | 0.62 |
| ▸ | ATM | Q13315 | 2/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.44 |
| ▸ | KDR | P35968 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.43 |
| ▸ | RAB9A | P51151 | 4/20 | 0.43 |
| ▸ | HPGD | P15428 | 4/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | ABL1 | P00519 | 1/20 | 0.43 |
| ▸ | FABP6 | P51161 | 1/20 | 0.43 |
| ▸ | UNG | P13051 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.42 |
| ▸ | MEN1 | O00255 | 3/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.42 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11069044 | 0.83 | ALDH1A1 (0.57) | KIF11ATMTDP1L3MBTL1ALDH1A1 | |
| Benzene SCHEMBL28184721 | 0.82 | KIF11 (0.81) | KIF11ALDH1A1RAB9AHPGDPOLB | |
| SCHEMBL23609063 | 0.82 | KIF11 (0.42) | KIF11ATMTDP1L3MBTL1CHEK1 | |
| SCHEMBL6299735 | 0.79 | KIF11 (0.81) | KIF11TDP1ALDH1A1RAB9AHPGD | |
| SCHEMBL2775335 | 0.77 | KIF11 (1.00) | KIF11ATMALDH1A1HPGDSMN1; SMN2 | |
| SCHEMBL29823607 | 0.77 | KIF11 (1.00) | KIF11ATMALDH1A1HPGDSMN1; SMN2 | |
| SCHEMBL13723964 | 0.77 | MAPT (0.49) | ATMTDP1L3MBTL1CHEK1KDR | |
| SCHEMBL1047541 | 0.77 | ALDH1A1 (0.64) | ATMTDP1L3MBTL1ALDH1A1RAB9A | |
| SCHEMBL18678667 | 0.77 | ALDH1A1 (0.64) | ATMTDP1L3MBTL1ALDH1A1RAB9A | |
| Benzene SCHEMBL28322201 | 0.77 | ALDH1A1 (0.64) | ATMTDP1L3MBTL1ALDH1A1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4483989-A | BENZOYLATION 6-HYDROXYCARBAZOLE, FORMYLATING, CYCLIZATION, AND SAPONIFICATION | AGENCE NATIONALE DE VALORISATION DE LA RECHERCHE (ANVAR) (FR) | 1984-11-20 | — | — | US | claimed |