Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 7/20 | 0.64 |
| ▸ | MEN1 | O00255 | 6/20 | 0.64 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.64 |
| ▸ | MAPT | P10636 | 7/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.50 |
| ▸ | MAPK1 | P28482 | 4/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 4/20 | 0.50 |
| ▸ | HTT | P42858 | 2/20 | 0.50 |
| ▸ | CXCR2 | P25025 | 4/20 | 0.49 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.47 |
| ▸ | HPGD | P15428 | 1/20 | 0.47 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 3/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.47 |
| ▸ | KIF11 | P52732 | 1/20 | 0.47 |
| ▸ | NPC1 | O15118 | 1/20 | 0.47 |
| ▸ | MITF | O75030 | 1/20 | 0.47 |
| ▸ | RAB9A | P51151 | 1/20 | 0.47 |
| ▸ | CASP7 | P55210 | 1/20 | 0.45 |
| ▸ | POLB | P06746 | 2/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11593456 | 0.90 | MEN1 (0.51) | KMT2AMEN1HSP90AA1MAPTALDH1A1 | |
| SCHEMBL11593897 | 0.89 | MAPT (0.54) | KMT2AMEN1HSP90AA1MAPTALDH1A1 | |
| SCHEMBL11137496 | 0.88 | MEN1 (0.49) | KMT2AMEN1HSP90AA1MAPTALDH1A1 | |
| SCHEMBL11587736 | 0.88 | MAPK1 (0.49) | KMT2AMEN1HSP90AA1MAPTALDH1A1 | |
| SCHEMBL11235688 | 0.87 | KIF11 (0.62) | KMT2AMEN1HSP90AA1MAPTMAPK1 | |
| SCHEMBL10527347 | 0.86 | MAPT (0.56) | KMT2AMEN1HSP90AA1MAPTALDH1A1 | |
| SCHEMBL11587443 | 0.86 | MEN1 (0.54) | KMT2AMEN1HSP90AA1MAPTALDH1A1 | |
| SCHEMBL11232334 | 0.86 | MAPT (0.59) | KMT2AMEN1HSP90AA1MAPTALDH1A1 | |
| SCHEMBL11587093 | 0.86 | MEN1 (0.48) | KMT2AMEN1HSP90AA1MAPTALDH1A1 | |
| SCHEMBL11587743 | 0.86 | MEN1 (0.48) | KMT2AMEN1HSP90AA1MAPTALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 18 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4459304-A | MITICIDES, NEMATOCIDES, FUNGICIDES, BACTERICIDES, INSECTICIDES | BAYER AKTIENGESELLSCHAFT (DE) | 1984-07-10 | — | — | US | claimed |
| US-4117167-A | INSECTICIDES, ACARICIDES | IMPERIAL CHEMICAL INDUSTRIES LIMITED (GB) | 1978-09-26 | — | — | US | claimed |
| US-4459304-A | MITICIDES, NEMATOCIDES, FUNGICIDES, BACTERICIDES, INSECTICIDES | BAYER AKTIENGESELLSCHAFT (DE) | 1984-07-10 | — | — | US | disclosed |
| US-4459304-A | MITICIDES, NEMATOCIDES, FUNGICIDES, BACTERICIDES, INSECTICIDES | BAYER AKTIENGESELLSCHAFT (DE) | 1984-07-10 | — | — | US | disclosed |
| US-4459304-A | MITICIDES, NEMATOCIDES, FUNGICIDES, BACTERICIDES, INSECTICIDES | BAYER AKTIENGESELLSCHAFT (DE) | 1984-07-10 | — | — | US | disclosed |
| US-4407820-A | INSECTICIDES, MITICIDES | ELI LILLY AND COMPANY (US) | 1983-10-04 | — | — | US | disclosed |
| EP-0026743-B1 | POLYSUBSTITUTED DIPHENYL AMINES, THEIR PREPARATION AND THEIR USE | CIBA-GEIGY AG (CH) | 1983-05-25 | — | — | EP | disclosed |
| EP-0060951-A1 | Improvements in or relating to N-alkylated diphenylamine derivatives | ELI LILLY AND COMPANY (US) | 1982-09-29 | — | — | EP | disclosed |
| US-4316988-A | CHEMICAL INTERMEDIATE FOR RODENTICIDAL DIPHENYLAMINES | ELI LILLY AND COMPANY (US) | 1982-02-23 | — | — | US | disclosed |
| US-4311710-A | Anticoccidial formulation and method | ELI LILLY AND COMPANY (US) | 1982-01-19 | — | — | US | disclosed |
| US-4309425-A | Miticidal, insecticidal, ovicidal and fungicidal N-(N',N'-diarylaminothio)sulfonamides | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 1982-01-05 | — | — | US | disclosed |
| US-4304791-A | INSECTICIDES, ANTIPROTOZOA AGENTS, AND PARASITICIDES | ELI LILLY AND COMPANY (US) | 1981-12-08 | — | — | US | disclosed |
| EP-0033580-A1 | Novel benzenamines, their preparation and fungicide and anticoccidial compositions containing them | ELI LILLY AND COMPANY (US) | 1981-08-12 | — | — | EP | disclosed |
| EP-0026743-A1 | Polysubstituted diphenyl amines, their preparation and their use | CIBA-GEIGY AG (CH) | 1981-04-08 | — | — | EP | disclosed |
| EP-0024906-A1 | Miticidal, insecticidal, ovicidal and fungicidal diarylaminothio derivatives, and preparation, compositions and use thereof | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 1981-03-11 | — | — | EP | disclosed |
| US-4187318-A | 2,4-DINITRO-6-TRIFLUOROMETHYL- | ELI LILLY AND COMPANY (US) | 1980-02-05 | — | — | US | disclosed |
| US-4117167-A | INSECTICIDES, ACARICIDES | IMPERIAL CHEMICAL INDUSTRIES LIMITED (GB) | 1978-09-26 | — | — | US | disclosed |
| US-4117167-A | INSECTICIDES, ACARICIDES | IMPERIAL CHEMICAL INDUSTRIES LIMITED (GB) | 1978-09-26 | — | — | US | disclosed |