Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KIF11 | P52732 | 1/20 | 0.62 |
| ▸ | MAPT | P10636 | 2/20 | 0.52 |
| ▸ | MPO | P05164 | 1/20 | 0.52 |
| ▸ | MEN1 | O00255 | 2/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.49 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.49 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.47 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.46 |
| ▸ | AKR1C4 | P17516 | 1/20 | 0.46 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.46 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.46 |
| ▸ | AKR1C1 | Q04828 | 1/20 | 0.46 |
| ▸ | ABCG2 | Q9UNQ0 | 3/20 | 0.46 |
| ▸ | FBP1 | P09467 | 1/20 | 0.46 |
| ▸ | RAPGEF4 | Q8WZA2 | 1/20 | 0.46 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.45 |
| ▸ | GRIK1 | P39086 | 1/20 | 0.44 |
| ▸ | ARNT | P27540 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11145707 | 0.92 | KIF11 (0.68) | KIF11MAPTMPOMEN1KMT2A | |
| SCHEMBL10801009 | 0.92 | KIF11 (0.58) | KIF11MAPTMPOMEN1KMT2A | |
| SCHEMBL11593897 | 0.90 | MAPT (0.54) | KIF11MAPTMPOMEN1KMT2A | |
| SCHEMBL11063459 | 0.87 | KMT2A (0.64) | KIF11MAPTMEN1KMT2AHSP90AA1 | |
| SCHEMBL11586472 | 0.87 | MEN1 (0.44) | KIF11MAPTMEN1KMT2AHSP90AA1 | |
| SCHEMBL11594805 | 0.86 | MAPT (0.51) | KIF11MAPTMPOMEN1KMT2A | |
| SCHEMBL11591552 | 0.86 | MAPT (0.51) | KIF11MAPTMEN1KMT2AHSP90AA1 | |
| SCHEMBL11592831 | 0.86 | MEN1 (0.54) | KIF11MAPTMEN1KMT2AHSP90AA1 | |
| SCHEMBL11587736 | 0.86 | MAPK1 (0.49) | KIF11MAPTMEN1KMT2AHSP90AA1 | |
| SCHEMBL11063352 | 0.84 | MAPT (0.49) | KIF11MAPTMEN1KMT2AHSP90AA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4117167-A | INSECTICIDES, ACARICIDES | IMPERIAL CHEMICAL INDUSTRIES LIMITED (GB) | 1978-09-26 | — | — | US | claimed |
| US-4316988-A | CHEMICAL INTERMEDIATE FOR RODENTICIDAL DIPHENYLAMINES | ELI LILLY AND COMPANY (US) | 1982-02-23 | — | — | US | disclosed |
| US-4117167-A | INSECTICIDES, ACARICIDES | IMPERIAL CHEMICAL INDUSTRIES LIMITED (GB) | 1978-09-26 | — | — | US | disclosed |