Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD2 | P14416 | 9/20 | 0.44 |
| ▸ | DRD3 | P35462 | 6/20 | 0.43 |
| ▸ | DRD4 | P21917 | 5/20 | 0.43 |
| ▸ | SLC6A1 | P30531 | 1/20 | 0.41 |
| ▸ | SLC6A12 | P48065 | 1/20 | 0.41 |
| ▸ | SLC6A11 | P48066 | 1/20 | 0.41 |
| ▸ | SLC6A13 | Q9NSD5 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | MAOA | P21397 | 3/20 | 0.41 |
| ▸ | MAOB | P27338 | 3/20 | 0.41 |
| ▸ | HTR1A | P08908 | 2/20 | 0.40 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.40 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.40 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.40 |
| ▸ | HTR2A | P28223 | 2/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11066546 | 0.89 | DRD2 (0.48) | DRD2DRD3DRD4SLC6A1SLC6A12 | |
| SCHEMBL11063280 | 0.87 | DRD2 (0.53) | DRD2DRD3DRD4HTR1AADRB2 | |
| SCHEMBL11071740 | 0.86 | HTR7 (0.50) | DRD2DRD3DRD4MAOAMAOB | |
| SCHEMBL11064025 | 0.85 | DRD2 (0.44) | DRD2DRD3DRD4KDM4EMAOA | |
| SCHEMBL11068604 | 0.84 | KCNH2 (0.53) | DRD2DRD3DRD4KDM4EHTR1A | |
| SCHEMBL11070967 | 0.83 | DRD2 (0.53) | DRD2DRD3DRD4MAOAMAOB | |
| SCHEMBL11064027 | 0.83 | DRD2 (0.48) | DRD2DRD3DRD4MAOAMAOB | |
| SCHEMBL11071326 | 0.82 | DRD2 (0.47) | DRD2DRD3DRD4MAOAMAOB | |
| SCHEMBL11065769 | 0.82 | DRD2 (0.58) | DRD2DRD3DRD4HTR1AADRB2 | |
| SCHEMBL11071420 | 0.82 | DRD2 (0.47) | DRD2DRD3DRD4HTR1AADRB2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4482560-A | Carbostyril derivatives, and antihistaminic agents containing the same | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1984-11-13 | — | — | US | disclosed |