Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNH2 | Q12809 | 3/20 | 0.53 |
| ▸ | DRD2 | P14416 | 10/20 | 0.44 |
| ▸ | DRD3 | P35462 | 4/20 | 0.44 |
| ▸ | DRD4 | P21917 | 2/20 | 0.44 |
| ▸ | HTR2A | P28223 | 5/20 | 0.44 |
| ▸ | HTR1A | P08908 | 3/20 | 0.44 |
| ▸ | HTR7 | P34969 | 2/20 | 0.44 |
| ▸ | DRD1 | P21728 | 1/20 | 0.44 |
| ▸ | DRD5 | P21918 | 1/20 | 0.44 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.44 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.44 |
| ▸ | HRH1 | P35367 | 1/20 | 0.44 |
| ▸ | HTR2B | P41595 | 1/20 | 0.44 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.43 |
| ▸ | TP53 | P04637 | 1/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.43 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.43 |
| ▸ | PKM | P14618 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11063280 | 0.92 | DRD2 (0.53) | KCNH2DRD2DRD3DRD4HTR2A | |
| SCHEMBL11071740 | 0.89 | HTR7 (0.50) | DRD2DRD3DRD4HTR2AHTR1A | |
| SCHEMBL11070769 | 0.89 | DRD2 (0.44) | KCNH2DRD2DRD3DRD4HTR1A | |
| SCHEMBL11064990 | 0.89 | DRD2 (0.51) | KCNH2DRD2DRD3DRD4HTR2A | |
| SCHEMBL11070967 | 0.87 | DRD2 (0.53) | DRD2DRD3DRD4HTR7SIGMAR1 | |
| SCHEMBL11068676 | 0.85 | KCNH2 (0.53) | KCNH2DRD2DRD3DRD4HTR2A | |
| SCHEMBL11071326 | 0.85 | DRD2 (0.47) | DRD2DRD3DRD4HTR2AHTR1A | |
| SCHEMBL11065769 | 0.85 | DRD2 (0.58) | KCNH2DRD2DRD3DRD4HTR2A | |
| SCHEMBL11071420 | 0.85 | DRD2 (0.47) | KCNH2DRD2DRD3DRD4HTR2A | |
| SCHEMBL11069074 | 0.84 | HTR7 (0.46) | DRD2DRD3DRD4HTR1AHTR7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4482560-A | Carbostyril derivatives, and antihistaminic agents containing the same | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1984-11-13 | — | — | US | disclosed |