Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | BCAT2 | O15382 | 1/20 | 0.46 |
| ▸ | GPR52 | Q9Y2T5 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | SCN1A | P35498 | 3/20 | 0.43 |
| ▸ | SCN2A | Q99250 | 3/20 | 0.43 |
| ▸ | SCN3A | Q9NY46 | 3/20 | 0.43 |
| ▸ | KDM2B | Q8NHM5 | 1/20 | 0.42 |
| ▸ | CHRNB2 | P17787 | 2/20 | 0.42 |
| ▸ | CHRNB4 | P30926 | 2/20 | 0.42 |
| ▸ | CHRNA3 | P32297 | 2/20 | 0.42 |
| ▸ | CHRNA4 | P43681 | 2/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | HNF4A | P41235 | 1/20 | 0.40 |
| ▸ | CNR1 | P21554 | 1/20 | 0.40 |
| ▸ | CNR2 | P34972 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | RECQL | P46063 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11063799 | 1.00 | MEN1 (0.46) | MEN1KMT2ASMN1; SMN2BCAT2GPR52 | |
| SCHEMBL10949032 | 0.80 | BCAT2 (0.55) | MEN1KMT2ASMN1; SMN2BCAT2GPR52 | |
| SCHEMBL10949037 | 0.80 | BCAT2 (0.55) | MEN1KMT2ASMN1; SMN2BCAT2GPR52 | |
| SCHEMBL2109360 | 0.78 | SMN1; SMN2 (0.53) | MEN1KMT2ASMN1; SMN2ALDH1A1L3MBTL1 | |
| SCHEMBL6259485 | 0.76 | AKR1C1 (0.50) | MEN1KMT2ASMN1; SMN2ALDH1A1LMNA | |
| SCHEMBL8041704 | 0.76 | AKR1C1 (0.50) | MEN1KMT2ASMN1; SMN2ALDH1A1LMNA | |
| SCHEMBL8041709 | 0.76 | AKR1C1 (0.50) | MEN1KMT2ASMN1; SMN2ALDH1A1LMNA | |
| SCHEMBL5421617 | 0.75 | BCAT2 (0.53) | MEN1KMT2ASMN1; SMN2BCAT2GPR52 | |
| SCHEMBL27992488 | 0.75 | CA9 (0.41) | MEN1KMT2ASMN1; SMN2BCAT2ALDH1A1 | |
| SCHEMBL28474385 | 0.74 | MEN1 (0.49) | MEN1KMT2ASMN1; SMN2BCAT2GPR52 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4536515-A | Substituted phenylalkenoic acids and esters | MERCK FROSST CANADA, INC. (CA) | 1985-08-20 | — | — | US | disclosed |