SCHEMBL28474385

SCHEMBL28474385

CO/C=C(/C(=O)O)c1ccccc1-c1ccccc1

nearest known ligand 0.49

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 2/20 0.49
KMT2A Q03164 2/20 0.49
SMN1; SMN2 Q16637 1/20 0.49
BCAT2 O15382 1/20 0.49
GAA P10253 2/20 0.46
POLB P06746 1/20 0.46
SLC6A3 Q01959 3/20 0.44
SLC6A4 P31645 2/20 0.44
CHRNB2 P17787 3/20 0.44
CHRNB4 P30926 3/20 0.44
CHRNA3 P32297 3/20 0.44
CHRNA4 P43681 3/20 0.44
KDM4E B2RXH2 1/20 0.43
HTT P42858 1/20 0.43
HNF4A P41235 1/20 0.42
ALDH1A1 P00352 1/20 0.42
TSHR P16473 1/20 0.41
RECQL P46063 1/20 0.41
SCN1A P35498 2/20 0.41
SCN2A Q99250 2/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8617249 0.87 GAA (0.47) MEN1KMT2ASMN1; SMN2BCAT2GAA
SCHEMBL8617255 0.87 GAA (0.47) MEN1KMT2ASMN1; SMN2BCAT2GAA
SCHEMBL28768175 0.87 GAA (0.47) MEN1KMT2ASMN1; SMN2BCAT2GAA
SCHEMBL10949032 0.82 BCAT2 (0.55) MEN1KMT2ASMN1; SMN2BCAT2GAA
SCHEMBL10949037 0.82 BCAT2 (0.55) MEN1KMT2ASMN1; SMN2BCAT2GAA
SCHEMBL7770355 0.79 ERCC5 (0.46) MEN1KMT2ASMN1; SMN2KDM4EALDH1A1
SCHEMBL3122880 0.79 LMNA (0.52) MEN1KMT2ASMN1; SMN2GAAKDM4E
SCHEMBL6265289 0.79 ERCC5 (0.46) MEN1KMT2ASMN1; SMN2KDM4EALDH1A1
SCHEMBL3122885 0.79 LMNA (0.52) MEN1KMT2ASMN1; SMN2GAAKDM4E
SCHEMBL4787172 0.79 LMNA (0.52) MEN1KMT2ASMN1; SMN2GAAKDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-109311830-B Microbicidal oxadiazole derivatives 先正达参股股份有限公司 2023-02-24 CN disclosed
CN-109195966-B Microbiocidal thiazole derivatives 先正达参股股份有限公司 2022-09-16 CN disclosed
CN-114340374-A Sowing device and method for treating seeds during planting 先正达参股股份有限公司 2022-04-12 CN disclosed
CN-114269145-A Apparatus and method for converting an existing sowing apparatus 先正达参股股份有限公司 2022-04-01 CN disclosed
CN-114269143-A High precision greenhouse treatment of seeds and seedlings 先正达参股股份有限公司 2022-04-01 CN disclosed
CN-114269144-A Precision processing and sowing or planting method and apparatus 先正达参股股份有限公司 2022-04-01 CN disclosed
CN-114258261-A Apparatus and method for reducing dust development in precision drilling 先正达参股股份有限公司 2022-03-29 CN disclosed
CN-107428722-B Microbicidal heterobicyclic derivatives 先正达参股股份有限公司 2021-04-20 CN disclosed
CN-111892576-A Microbicidal heterobicyclic derivatives 先正达参股股份有限公司 2020-11-06 CN disclosed