Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.44 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.42 |
| ▸ | RAB9A | P51151 | 5/20 | 0.40 |
| ▸ | POLB | P06746 | 2/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.40 |
| ▸ | PTPRC | P08575 | 3/20 | 0.40 |
| ▸ | S100A4 | P26447 | 2/20 | 0.40 |
| ▸ | BCHE | P06276 | 1/20 | 0.40 |
| ▸ | ACHE | P22303 | 1/20 | 0.40 |
| ▸ | CES1 | P23141 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 4/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.39 |
| ▸ | MAPT | P10636 | 3/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | GAA | P10253 | 2/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11063998 | 0.90 | PTGS2 (0.43) | ALDH1A1PTGS2RAB9APOLBTDP1 | |
| SCHEMBL10733203 | 0.76 | TTR (0.41) | ALDH1A1POLBTDP1PTPRCBCHE | |
| SCHEMBL11067177 | 0.75 | MEN1 (0.43) | ALDH1A1PTGS2RAB9APOLBTDP1 | |
| SCHEMBL5925223 | 0.75 | ALDH1A1 (0.53) | ALDH1A1PTGS2RAB9APOLBTDP1 | |
| SCHEMBL11287364 | 0.73 | ALDH1A1 (0.44) | ALDH1A1RAB9APOLBTDP1PTPRC | |
| SCHEMBL16586317 | 0.73 | TDP1 (0.55) | ALDH1A1PTGS2RAB9APOLBTDP1 | |
| SCHEMBL6775236 | 0.71 | PTGS2 (0.54) | ALDH1A1PTGS2RAB9APOLBTDP1 | |
| SCHEMBL2437022 | 0.71 | CRHBP (0.55) | ALDH1A1PTGS2RAB9APOLBTDP1 | |
| SCHEMBL6391559 | 0.69 | PTGS2 (0.69) | ALDH1A1PTGS2RAB9APOLBTDP1 | |
| SCHEMBL28207049 | 0.69 | PTGS2 (0.73) | ALDH1A1PTGS2RAB9APOLBTDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4480105-A | PHOTOCROSSLINKING POLYMERS | CIBA-GEIGY CORPORATION (US) | 1984-10-30 | — | — | US | disclosed |
| US-4385182-A | SENSITIZERS OR PHOTOINITIATORS | CIBA-GEIGY CORPORATION (US) | 1983-05-24 | — | — | US | disclosed |
| US-4363917-A | SENSITIZERS FOR PHOTOCROSSLINKABLE POLYMERS; PHOTOPOLYMERIZATION INITIATORS | CIBA-GEIGY CORPORATION (US) | 1982-12-14 | — | — | US | disclosed |