Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TP53 | P04637 | 1/20 | 0.43 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.42 |
| ▸ | NPC1 | O15118 | 2/20 | 0.42 |
| ▸ | RAB9A | P51151 | 2/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | HPGD | P15428 | 2/20 | 0.42 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.41 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.40 |
| ▸ | CTNNB1 | P35222 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11075790 | 0.85 | NR4A2 (0.49) | KDM4ENPC1RAB9AALDH1A1HPGD | |
| SCHEMBL11306407 | 0.83 | GAA (0.45) | KDM4ENPC1RAB9AALDH1A1HPGD | |
| SCHEMBL11070198 | 0.83 | ALDH1A1 (0.48) | TP53RXFP1KDM4ENPC1RAB9A | |
| SCHEMBL11073671 | 0.82 | EGFR (0.54) | TP53NPC1RAB9AALDH1A1HPGD | |
| SCHEMBL10832665 | 0.80 | AKR1C3 (0.45) | KDM4ENPC1RAB9AALDH1A1HPGD | |
| SCHEMBL370664 | 0.79 | AKR1C3 (0.44) | KDM4ENPC1RAB9AALDH1A1HPGD | |
| SCHEMBL877659 | 0.77 | AKR1C3 (0.59) | KDM4ENPC1RAB9AALDH1A1HPGD | |
| SCHEMBL11073937 | 0.77 | SLC7A5 (0.47) | TP53KDM4ENPC1RAB9AALDH1A1 | |
| SCHEMBL11704492 | 0.76 | ALDH1A1 (0.52) | KDM4ENPC1RAB9AALDH1A1FFAR1 | |
| SCHEMBL370685 | 0.76 | HCAR3 (0.44) | KDM4ENPC1RAB9AKMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4440940-A | HYPOLIPIDEMIC AND ANTIATHEROSCLEROTIC AGENTS | AMERICAN CYANAMID COMPANY (US) | 1984-04-03 | — | — | US | disclosed |