Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EGFR | P00533 | 1/20 | 0.54 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.54 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.54 |
| ▸ | RAB9A | P51151 | 4/20 | 0.54 |
| ▸ | POLB | P06746 | 1/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.52 |
| ▸ | NPC1 | O15118 | 3/20 | 0.52 |
| ▸ | MAPT | P10636 | 2/20 | 0.52 |
| ▸ | TCF4 | P15884 | 2/20 | 0.50 |
| ▸ | CTNNB1 | P35222 | 2/20 | 0.50 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.50 |
| ▸ | HPGD | P15428 | 1/20 | 0.49 |
| ▸ | TP53 | P04637 | 1/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.49 |
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.49 |
| ▸ | MEN1 | O00255 | 2/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.48 |
| ▸ | ABL1 | P00519 | 1/20 | 0.48 |
| ▸ | RIN1 | Q13671 | 1/20 | 0.48 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11155678 | 0.87 | KMT2A (0.56) | MAPK1HSD17B10RAB9APOLBALDH1A1 | |
| SCHEMBL11450535 | 0.84 | KDM4E (0.49) | HSD17B10POLBALDH1A1MAPTHIF1A | |
| SCHEMBL1671869 | 0.84 | EGFR (0.53) | EGFRMAPK1HSD17B10RAB9APOLB | |
| SCHEMBL877659 | 0.83 | AKR1C3 (0.59) | RAB9APOLBALDH1A1NPC1MAPT | |
| SCHEMBL694377 | 0.82 | EGFR (0.52) | EGFRMAPK1HSD17B10RAB9APOLB | |
| SCHEMBL11064077 | 0.82 | TP53 (0.43) | EGFRMAPK1HSD17B10RAB9AALDH1A1 | |
| SCHEMBL20391310 | 0.81 | EGFR (0.54) | EGFRMAPK1HSD17B10RAB9APOLB | |
| SCHEMBL25174147 | 0.81 | RAB9A (0.59) | EGFRMAPK1HSD17B10RAB9APOLB | |
| SCHEMBL30445248 | 0.81 | RAB9A (0.59) | EGFRMAPK1HSD17B10RAB9APOLB | |
| SCHEMBL1458957 | 0.81 | MEN1 (0.59) | MAPK1RAB9APOLBALDH1A1NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4440940-A | HYPOLIPIDEMIC AND ANTIATHEROSCLEROTIC AGENTS | AMERICAN CYANAMID COMPANY (US) | 1984-04-03 | — | — | US | disclosed |