Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.55 |
| ▸ | NPC1 | O15118 | 4/20 | 0.55 |
| ▸ | RAB9A | P51151 | 4/20 | 0.55 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.55 |
| ▸ | HTT | P42858 | 3/20 | 0.55 |
| ▸ | PAX8 | Q06710 | 3/20 | 0.55 |
| ▸ | GLA | P06280 | 2/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.48 |
| ▸ | MEN1 | O00255 | 2/20 | 0.48 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.48 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.48 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.48 |
| ▸ | TSHR | P16473 | 2/20 | 0.48 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.48 |
| ▸ | POLB | P06746 | 1/20 | 0.48 |
| ▸ | JAK2 | O60674 | 1/20 | 0.47 |
| ▸ | TP53 | P04637 | 3/20 | 0.47 |
| ▸ | EGFR | P00533 | 1/20 | 0.46 |
| ▸ | ERBB2 | P04626 | 1/20 | 0.46 |
| ▸ | TRPM8 | Q7Z2W7 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8041935 | 0.84 | ALDH1A1 (0.50) | ALDH1A1NPC1RAB9ASMN1; SMN2HTT | |
| SCHEMBL5154776 | 0.83 | ADRA2C (0.55) | ALDH1A1NPC1RAB9ASMN1; SMN2HTT | |
| SCHEMBL11287043 | 0.83 | ALDH1A1 (0.58) | ALDH1A1NPC1RAB9ASMN1; SMN2HTT | |
| SCHEMBL15904567 | 0.82 | ALDH1A1 (0.39) | ALDH1A1NPC1RAB9ASMN1; SMN2HTT | |
| SCHEMBL1491953 | 0.82 | ADRA2C (0.65) | ALDH1A1NPC1RAB9ASMN1; SMN2HTT | |
| SCHEMBL4935083 | 0.82 | ALDH1A1 (0.54) | ALDH1A1NPC1RAB9ASMN1; SMN2HTT | |
| SCHEMBL17333385 | 0.81 | TP53 (0.59) | ALDH1A1NPC1RAB9ASMN1; SMN2HTT | |
| SCHEMBL17473048 | 0.81 | NPC1 (0.57) | ALDH1A1NPC1RAB9ASMN1; SMN2HTT | |
| SCHEMBL30957362 | 0.81 | NPC1 (0.57) | ALDH1A1NPC1RAB9ASMN1; SMN2HTT | |
| SCHEMBL7791465 | 0.81 | HDAC3 (0.51) | ALDH1A1NPC1RAB9ASMN1; SMN2HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4487952-A | CARBONYLATION OF AROMATIC NITRO COMPOUNDS | ANIC S.P.A. (IT) | 1984-12-11 | — | — | US | disclosed |
| US-4202684-A | Carbanilic acid esters, process for making the same and herbicidal compositions containing same | SCHERING AKTIENGESELLSCHAFT (DE) | 1980-05-13 | — | — | US | disclosed |