Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRA2C | P18825 | 1/20 | 0.55 |
| ▸ | NPC1 | O15118 | 3/20 | 0.54 |
| ▸ | RAB9A | P51151 | 3/20 | 0.54 |
| ▸ | PAX8 | Q06710 | 2/20 | 0.54 |
| ▸ | JAK2 | O60674 | 1/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.52 |
| ▸ | GLA | P06280 | 2/20 | 0.52 |
| ▸ | TSHR | P16473 | 2/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.52 |
| ▸ | MEN1 | O00255 | 2/20 | 0.52 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.52 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.52 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.52 |
| ▸ | HTT | P42858 | 4/20 | 0.50 |
| ▸ | TP53 | P04637 | 1/20 | 0.50 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | TRPM8 | Q7Z2W7 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17473048 | 0.98 | NPC1 (0.57) | ADRA2CNPC1RAB9APAX8JAK2 | |
| SCHEMBL30957362 | 0.98 | NPC1 (0.57) | ADRA2CNPC1RAB9APAX8JAK2 | |
| SCHEMBL894066 | 0.90 | NPC1 (0.69) | ADRA2CNPC1RAB9APAX8JAK2 | |
| SCHEMBL4918307 | 0.90 | ADRA2C (0.50) | ADRA2CNPC1RAB9APAX8JAK2 | |
| SCHEMBL5509984 | 0.89 | NPC1 (0.71) | ADRA2CNPC1RAB9APAX8JAK2 | |
| SCHEMBL7995028 | 0.89 | NPC1 (0.71) | ADRA2CNPC1RAB9APAX8JAK2 | |
| SCHEMBL8032558 | 0.89 | NPC1 (0.71) | ADRA2CNPC1RAB9APAX8JAK2 | |
| SCHEMBL7469093 | 0.89 | NPC1 (0.71) | ADRA2CNPC1RAB9APAX8JAK2 | |
| SCHEMBL2892022 | 0.88 | NPC1 (0.61) | ADRA2CNPC1RAB9APAX8JAK2 | |
| SCHEMBL7791465 | 0.84 | HDAC3 (0.51) | ADRA2CNPC1RAB9APAX8ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1226209-B1 | A COMBINATION OF A SOLID SOLVENT AND A MELT-PROCESSIBLE BLOCK COPOLYMER | GORE ENTERPRISE HOLDINGS INC (US) | 2007-01-10 | — | — | EP | disclosed |
| US-6387994-B1 | MIXTURES | W. L. GORE & ASSOCIATES, INC. | 2002-05-14 | — | — | US | disclosed |