SCHEMBL11064216

SCHEMBL11064216

CSc1ccc(C)cc1CO

nearest known ligand 0.42

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALOX15 P16050 2/20 0.42
HSD17B10 Q99714 2/20 0.42
MEN1 O00255 2/20 0.42
MAPT P10636 2/20 0.42
KMT2A Q03164 2/20 0.42
LMNA P02545 1/20 0.42
TP53 P04637 1/20 0.42
GAA P10253 1/20 0.42
HPGD P15428 1/20 0.42
ALOX12 P18054 1/20 0.42
AMY1A P0DUB6 1/20 0.37
NPC1 O15118 1/20 0.37
RAB9A P51151 1/20 0.37
TAAR1 Q96RJ0 1/20 0.35
SLC6A4 P31645 6/20 0.35
ADRA2A P08913 1/20 0.35
ADRA2B P18089 1/20 0.35
ADRA2C P18825 1/20 0.35
ADRA1D P25100 1/20 0.35
ADRA1A P35348 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL19622316 0.83 ALOX15 (0.38) ALOX15HSD17B10MEN1MAPTKMT2A
SCHEMBL11759425 0.82 SLC6A4 (0.44) ALOX15HSD17B10MEN1MAPTKMT2A
SCHEMBL18508629 0.81 MAPT (0.39) ALOX15HSD17B10MEN1MAPTKMT2A
SCHEMBL11578003 0.79 MAPT (0.50) ALOX15HSD17B10MEN1MAPTKMT2A
Hydrochloric Acid SCHEMBL1013629 0.78 SLC6A4 (0.47) ALOX15HSD17B10MEN1MAPTKMT2A
SCHEMBL16952861 0.78 SLC6A4 (0.54) MEN1MAPTKMT2ALMNANPC1
SCHEMBL7695636 0.78 PRKCI (0.39) MAPTGAASLC6A4ALDH1A1APOBEC3G
SCHEMBL16958867 0.78 SLC6A4 (0.54) ALOX15HSD17B10MEN1MAPTKMT2A
SCHEMBL18149272 0.77 MAPT (0.33) ALOX15HSD17B10MEN1MAPTKMT2A
SCHEMBL11702988 0.77 HTR1A (0.49) MAPTTP53SLC6A4ALDH1A1SLC6A2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2900645-A1 3-PHENYLISOXAZOLIN DERIVATIVES WITH HERBICIDAL ACTION Bayer CropScience AG (DE) 2015-08-05 EP disclosed
US-20110081597-A1 POLYMER ELECTROLYTE, CROSSLINKED POLYMER ELECTROLYTE, POLYMER ELECTROLYTE MEMBRANE AND USE OF THE SAME SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2011-04-07 US disclosed
US-4436804-A Light-sensitive polymeric diazonium condensates and reproduction compositions and materials therewith AMERICAN HOECHST CORPORATION (US) 1984-03-13 US disclosed