Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KIF11 | P52732 | 6/20 | 0.40 |
| ▸ | PIM3 | Q86V86 | 2/20 | 0.38 |
| ▸ | MAPT | P10636 | 3/20 | 0.37 |
| ▸ | JAK2 | O60674 | 1/20 | 0.37 |
| ▸ | TP53 | P04637 | 1/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | KLK7 | P49862 | 1/20 | 0.37 |
| ▸ | CDK4 | P11802 | 4/20 | 0.36 |
| ▸ | CCND1 | P24385 | 4/20 | 0.36 |
| ▸ | GABRP | O00591 | 2/20 | 0.35 |
| ▸ | GABRD | O14764 | 2/20 | 0.35 |
| ▸ | GABRA1 | P14867 | 2/20 | 0.35 |
| ▸ | GABRB1 | P18505 | 2/20 | 0.35 |
| ▸ | GABRG2 | P18507 | 2/20 | 0.35 |
| ▸ | GABRB3 | P28472 | 2/20 | 0.35 |
| ▸ | GABRA5 | P31644 | 2/20 | 0.35 |
| ▸ | GABRA3 | P34903 | 2/20 | 0.35 |
| ▸ | GABRA2 | P47869 | 2/20 | 0.35 |
| ▸ | GABRB2 | P47870 | 2/20 | 0.35 |
| ▸ | GABRA4 | P48169 | 2/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29010543 | 0.78 | KIF11 (0.40) | KIF11PIM3MAPTJAK2TP53 | |
| SCHEMBL29895701 | 0.75 | KIF11 (0.50) | KIF11PIM3MAPTJAK2TP53 | |
| SCHEMBL2181837 | 0.75 | KIF11 (0.50) | KIF11PIM3MAPTJAK2TP53 | |
| SCHEMBL29940531 | 0.75 | KIF11 (0.50) | KIF11PIM3MAPTJAK2TP53 | |
| SCHEMBL31661008 | 0.72 | DYRK1A (0.40) | KIF11MAPTJAK2TP53HTT | |
| SCHEMBL20135926 | 0.71 | TDO2 (0.51) | KIF11MAPTGABRPGABRDGABRA1 | |
| SCHEMBL15453693 | 0.71 | KIF11 (0.63) | KIF11MAPTCDK4CCND1MEN1 | |
| Sulfuric Acid SCHEMBL28215212 | 0.69 | KIF11 (0.45) | KIF11PIM3MAPTJAK2TP53 | |
| Sulfuric Acid SCHEMBL28215214 | 0.69 | KIF11 (0.45) | KIF11PIM3MAPTJAK2TP53 | |
| SCHEMBL9271477 | 0.67 | KIF11 (0.53) | KIF11PIM3MAPTJAK2TP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4482489-A | USEFUL IN DIAZOTYPE SYSTEMS AND AS LATENT POLYMERIZATION INITIATORS | JAMES RIVER GRAPHICS, INC. (US) | 1984-11-13 | — | — | US | claimed |
| US-4482489-A | USEFUL IN DIAZOTYPE SYSTEMS AND AS LATENT POLYMERIZATION INITIATORS | JAMES RIVER GRAPHICS, INC. (US) | 1984-11-13 | — | — | US | disclosed |