Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DYRK1A | Q13627 | 4/20 | 0.40 |
| ▸ | CLK1 | P49759 | 2/20 | 0.40 |
| ▸ | PDE9A | O76083 | 5/20 | 0.38 |
| ▸ | GABRP | O00591 | 1/20 | 0.38 |
| ▸ | GABRD | O14764 | 1/20 | 0.38 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.38 |
| ▸ | GABRB1 | P18505 | 1/20 | 0.38 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.38 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.38 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.38 |
| ▸ | GABRA3 | P34903 | 1/20 | 0.38 |
| ▸ | GABRA2 | P47869 | 1/20 | 0.38 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.38 |
| ▸ | GABRA4 | P48169 | 1/20 | 0.38 |
| ▸ | GABRE | P78334 | 1/20 | 0.38 |
| ▸ | GABRA6 | Q16445 | 1/20 | 0.38 |
| ▸ | GABRG1 | Q8N1C3 | 1/20 | 0.38 |
| ▸ | GABRG3 | Q99928 | 1/20 | 0.38 |
| ▸ | GABRQ | Q9UN88 | 1/20 | 0.38 |
| ▸ | CDK5 | Q00535 | 3/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7589144 | 0.76 | ALDH1A1 (0.38) | PDE9AMAPTKDM4EALDH1A1HPGD | |
| SCHEMBL11064259 | 0.72 | KIF11 (0.40) | GABRPGABRDGABRA1GABRB1GABRG2 | |
| SCHEMBL29940531 | 0.71 | KIF11 (0.50) | GABRPGABRDGABRA1GABRB1GABRG2 | |
| SCHEMBL29895701 | 0.71 | KIF11 (0.50) | GABRPGABRDGABRA1GABRB1GABRG2 | |
| SCHEMBL2181837 | 0.71 | KIF11 (0.50) | GABRPGABRDGABRA1GABRB1GABRG2 | |
| SCHEMBL29010543 | 0.70 | KIF11 (0.40) | GABRPGABRDGABRA1GABRB1GABRG2 | |
| SCHEMBL31271695 | 0.69 | IMPDH2 (0.46) | GABRPGABRDGABRA1GABRB1GABRG2 | |
| SCHEMBL2181616 | 0.69 | IMPDH2 (0.46) | GABRPGABRDGABRA1GABRB1GABRG2 | |
| SCHEMBL7592910 | 0.68 | PDE4A (0.36) | DYRK1ACLK1MAPTKDM4EALDH1A1 | |
| SCHEMBL20135926 | 0.68 | TDO2 (0.51) | GABRPGABRDGABRA1GABRB1GABRG2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20250228853-A1 | Apoptosis Inhibitors | QUEEN'S UNIVERSITY AT KINGSTON (CA) | 2025-07-17 | — | — | US | claimed |
| US-20250228853-A1 | Apoptosis Inhibitors | QUEEN'S UNIVERSITY AT KINGSTON (CA) | 2025-07-17 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20250228853-A1 | Apoptosis Inhibitors | AIFM1, BAX, AIFM2 | DYRK1A 4695/4885CLK1 2533/4885PDE9A 4278/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.