Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.45 |
| ▸ | MAPT | P10636 | 2/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.45 |
| ▸ | SOS1 | Q07889 | 3/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.44 |
| ▸ | MET | P08581 | 1/20 | 0.43 |
| ▸ | HRH3 | Q9Y5N1 | 3/20 | 0.42 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.40 |
| ▸ | MAOA | P21397 | 1/20 | 0.39 |
| ▸ | MAOB | P27338 | 1/20 | 0.39 |
| ▸ | UTS2R | Q9UKP6 | 3/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | FPR2 | P25090 | 1/20 | 0.39 |
| ▸ | PROKR1 | Q8TCW9 | 1/20 | 0.39 |
| ▸ | SCD | O00767 | 1/20 | 0.38 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.38 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.38 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.38 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL11067172 | 0.99 | SMN1; SMN2 (0.46) | KDM4EMAPTLMNANPSR1SOS1 | |
| Hydrochloric Acid SCHEMBL11065086 | 0.83 | HRH3 (0.36) | KDM4EMAPTLMNANPSR1SOS1 | |
| SCHEMBL11064624 | 0.82 | HRH1 (0.50) | SOS1KCNH2 | |
| Hydrochloric Acid SCHEMBL11065701 | 0.81 | HRH1 (0.49) | SOS1KCNH2 | |
| SCHEMBL11072794 | 0.78 | KCNH2 (0.42) | MAPTLMNANPSR1KCNH2CHRM2 | |
| SCHEMBL11066536 | 0.75 | MEN1 (0.43) | SOS1HRH3KCNH2 | |
| SCHEMBL11066882 | 0.74 | CYP2J2 (0.51) | LMNAKCNH2ALDH1A1CHRM2CHRM4 | |
| SCHEMBL5542451 | 0.74 | KDM4E (0.64) | KDM4EMAPTLMNANPSR1SMN1; SMN2 | |
| SCHEMBL5541792 | 0.73 | MET (0.48) | KDM4EMAPTSMN1; SMN2METHRH3 | |
| SCHEMBL22278017 | 0.73 | HRH3 (0.48) | KDM4EMAPTLMNANPSR1SOS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4443462-A | Antipsychotic 4-(naphthalenyloxy)piperidine derivatives | MERRELL DOW PHARMACEUTICALS INC. (US) | 1984-04-17 | — | — | US | disclosed |