Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 4/20 | 0.70 |
| ▸ | NPC1 | O15118 | 2/20 | 0.70 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.66 |
| ▸ | MAPT | P10636 | 4/20 | 0.66 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.66 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.66 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.66 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.66 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.66 |
| ▸ | HTT | P42858 | 1/20 | 0.66 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.66 |
| ▸ | FAAH | O00519 | 3/20 | 0.66 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.65 |
| ▸ | MAPK1 | P28482 | 4/20 | 0.60 |
| ▸ | LMNA | P02545 | 2/20 | 0.60 |
| ▸ | MEN1 | O00255 | 2/20 | 0.60 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.60 |
| ▸ | ATM | Q13315 | 1/20 | 0.59 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.59 |
| ▸ | AR | P10275 | 3/20 | 0.59 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11076858 | 0.87 | RAB9A (0.66) | RAB9ANPC1ALDH1A1MAPTSMN1; SMN2 | |
| SCHEMBL11068460 | 0.87 | RAB9A (0.69) | RAB9ANPC1ALDH1A1MAPTSMN1; SMN2 | |
| SCHEMBL18674602 | 0.86 | RAB9A (0.75) | RAB9ANPC1ALDH1A1MAPTSMN1; SMN2 | |
| SCHEMBL3761593 | 0.85 | RAB9A (0.74) | RAB9ANPC1ALDH1A1MAPTSMN1; SMN2 | |
| SCHEMBL11072041 | 0.85 | RAB9A (0.67) | RAB9ANPC1ALDH1A1MAPTSMN1; SMN2 | |
| SCHEMBL11067938 | 0.85 | RAB9A (0.64) | RAB9ANPC1ALDH1A1MAPTSMN1; SMN2 | |
| SCHEMBL3766124 | 0.84 | MAPT (0.66) | RAB9ANPC1ALDH1A1MAPTSMN1; SMN2 | |
| SCHEMBL3764162 | 0.83 | FAAH (0.66) | RAB9ANPC1ALDH1A1MAPTSMN1; SMN2 | |
| SCHEMBL11064658 | 0.83 | RAB9A (0.71) | RAB9ANPC1ALDH1A1MAPTSMN1; SMN2 | |
| SCHEMBL11068190 | 0.83 | MEN1 (0.62) | RAB9ANPC1ALDH1A1MAPTSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4476128-A | ANTIARTHRITIC AGENTS ANTIBODY INHIBITORS | MITSUITOATSU CHEMICALS, INC. (JP) | 1984-10-09 | — | — | US | disclosed |