Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOA | P21397 | 10/20 | 0.63 |
| ▸ | MAOB | P27338 | 10/20 | 0.63 |
| ▸ | PDE3B | Q13370 | 4/20 | 0.51 |
| ▸ | PDE3A | Q14432 | 4/20 | 0.51 |
| ▸ | OGT | O15294 | 1/20 | 0.47 |
| ▸ | HTR1A | P08908 | 2/20 | 0.47 |
| ▸ | DRD2 | P14416 | 2/20 | 0.47 |
| ▸ | HTR2A | P28223 | 2/20 | 0.47 |
| ▸ | HTR2C | P28335 | 2/20 | 0.47 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.47 |
| ▸ | HTR7 | P34969 | 2/20 | 0.47 |
| ▸ | DRD3 | P35462 | 2/20 | 0.47 |
| ▸ | DRD4 | P21917 | 1/20 | 0.47 |
| ▸ | KDM1A | O60341 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11063106 | 0.91 | MAOA (0.61) | MAOAMAOBPDE3BPDE3AOGT | |
| SCHEMBL11064423 | 0.85 | MAOA (0.56) | MAOAMAOBPDE3BPDE3AHTR1A | |
| SCHEMBL11058875 | 0.84 | MAOA (0.65) | MAOAMAOBPDE3BPDE3AHTR1A | |
| SCHEMBL11065270 | 0.84 | MAOA (0.65) | MAOAMAOBPDE3BPDE3AHTR1A | |
| SCHEMBL11062029 | 0.83 | MAOA (0.55) | MAOAMAOBPDE3BPDE3AHTR1A | |
| Ethylbenzene SCHEMBL11064674 | 0.82 | MAOA (0.59) | MAOAMAOBPDE3BPDE3AHTR1A | |
| SCHEMBL11067768 | 0.82 | PDE3B (0.63) | MAOAMAOBPDE3BPDE3AHTR1A | |
| SCHEMBL11068252 | 0.82 | DRD2 (0.62) | MAOAMAOBPDE3BPDE3AHTR1A | |
| SCHEMBL11062067 | 0.79 | DRD2 (0.64) | MAOAMAOBPDE3BPDE3AHTR1A | |
| Ethylbenzene SCHEMBL11065281 | 0.79 | MAOA (0.57) | MAOAMAOBPDE3BPDE3AHTR1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4435404-A | ANTICOAGULANTS | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1984-03-06 | — | — | US | disclosed |