Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RCE1 | Q9Y256 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.37 |
| ▸ | MAPT | P10636 | 2/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | TP53 | P04637 | 1/20 | 0.34 |
| ▸ | CRBN | Q96SW2 | 1/20 | 0.34 |
| ▸ | PSIP1 | O75475 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.33 |
| ▸ | USP2 | O75604 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.32 |
| ▸ | CASP1 | P29466 | 1/20 | 0.32 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.32 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.32 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11173561 | 0.79 | ALDH1A1 (0.46) | RCE1ALDH1A1KMT2AMAPTKDM4E | |
| SCHEMBL11064709 | 0.77 | KMT2A (0.43) | ALDH1A1KMT2AMAPTKDM4EMEN1 | |
| SCHEMBL8617268 | 0.76 | CYP1A2 (0.39) | ALDH1A1KMT2A | |
| SCHEMBL27029593 | 0.71 | CYP1A2 (0.39) | ALDH1A1KMT2AKDM4EGAAHPGD | |
| SCHEMBL10911034 | 0.70 | PSIP1 (0.42) | RCE1ALDH1A1KMT2AMAPTKDM4E | |
| SCHEMBL14949718 | 0.68 | CYP2C19 (0.41) | ALDH1A1POLB | |
| SCHEMBL2444476 | 0.68 | PSIP1 (0.59) | ALDH1A1KMT2AMEN1GAAPOLB | |
| SCHEMBL5688628 | 0.68 | GRM2 (0.45) | ALDH1A1POLBCRBN | |
| SCHEMBL28601640 | 0.67 | SMN1; SMN2 (0.44) | ALDH1A1KMT2AMAPTKDM4EMEN1 | |
| SCHEMBL10989914 | 0.65 | MMP13 (0.38) | ALDH1A1KMT2AMAPTKDM4EGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4454351-A | Lactonic derivatives and use of same as starting materials for the preparation of macrocyclic hydroxyketones | FIRMENICH SA (CH) | 1984-06-12 | — | — | US | disclosed |
| US-4431827-A | Pentadecanolide derivatives | FIRMENICH S.A. (CH) | 1984-02-14 | — | — | US | disclosed |