Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRMT5 | O14744 | 2/20 | 0.47 |
| ▸ | WDR77 | Q9BQA1 | 2/20 | 0.47 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.46 |
| ▸ | DRD2 | P14416 | 4/20 | 0.46 |
| ▸ | DRD4 | P21917 | 4/20 | 0.46 |
| ▸ | DRD3 | P35462 | 4/20 | 0.46 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.46 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.46 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.46 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.46 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.46 |
| ▸ | HTR7 | P34969 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | PKM | P14618 | 1/20 | 0.43 |
| ▸ | SLC18A3 | Q16572 | 1/20 | 0.43 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11065731 | 0.88 | DRD4 (0.58) | DRD2DRD4DRD3CHRM2CHRM4 | |
| SCHEMBL11068145 | 0.88 | KCNH2 (0.49) | KCNH2 | |
| SCHEMBL11072463 | 0.86 | DRD2 (0.46) | PRMT5WDR77KCNH2DRD2DRD4 | |
| SCHEMBL11071842 | 0.86 | SLC18A3 (0.48) | PRMT5WDR77KCNH2DRD2DRD4 | |
| SCHEMBL11068538 | 0.85 | CHRM2 (0.57) | DRD2DRD4DRD3CHRM2CHRM4 | |
| SCHEMBL11067546 | 0.83 | KCNH2 (0.52) | KCNH2DRD2DRD4DRD3CHRM2 | |
| SCHEMBL11070374 | 0.78 | CHRM1 (0.52) | KCNH2DRD2DRD4DRD3CHRM2 | |
| SCHEMBL11063819 | 0.78 | CHRM2 (0.46) | DRD2DRD4DRD3CHRM2CHRM4 | |
| SCHEMBL11073822 | 0.78 | KCNH2 (0.54) | PRMT5WDR77KCNH2DRD2 | |
| SCHEMBL11066226 | 0.77 | DRD4 (0.62) | DRD4GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4482560-A | Carbostyril derivatives, and antihistaminic agents containing the same | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1984-11-13 | — | — | US | disclosed |