Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD4 | P21917 | 6/20 | 0.58 |
| ▸ | GAA | P10253 | 1/20 | 0.55 |
| ▸ | POLB | P06746 | 1/20 | 0.51 |
| ▸ | TSHR | P16473 | 1/20 | 0.51 |
| ▸ | ABCB1 | P08183 | 4/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.48 |
| ▸ | MEN1 | O00255 | 2/20 | 0.48 |
| ▸ | DRD2 | P14416 | 2/20 | 0.48 |
| ▸ | ATM | Q13315 | 1/20 | 0.47 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.47 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.47 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.47 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.47 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.47 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.47 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.47 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.47 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.47 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.47 |
| ▸ | DRD3 | P35462 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11066226 | 0.90 | DRD4 (0.62) | DRD4GAAPOLBTSHRKMT2A | |
| SCHEMBL11064740 | 0.88 | PRMT5 (0.47) | DRD4GAADRD2CHRM2CHRM4 | |
| SCHEMBL11069003 | 0.86 | DRD4 (0.62) | DRD4GAAPOLBTSHRABCB1 | |
| SCHEMBL11068257 | 0.85 | ADRB2 (0.59) | DRD4DRD2ADRB2CHRM2CHRM4 | |
| SCHEMBL11065197 | 0.80 | DRD4 (0.52) | DRD4DRD2ADRB2CHRM2CHRM4 | |
| SCHEMBL11068145 | 0.79 | KCNH2 (0.49) | — | |
| SCHEMBL11071360 | 0.78 | MAOA (0.69) | DRD4GAAPOLBTSHRABCB1 | |
| SCHEMBL11069966 | 0.77 | DRD4 (0.63) | DRD4GAAPOLBTSHRABCB1 | |
| SCHEMBL10578077 | 0.76 | HTR7 (0.63) | KMT2A | |
| SCHEMBL10660200 | 0.75 | HTR7 (0.48) | DRD4KMT2ADRD2ADRB2CHRM2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4482560-A | Carbostyril derivatives, and antihistaminic agents containing the same | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1984-11-13 | — | — | US | disclosed |