Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNH2 | Q12809 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11063819 | 0.90 | CHRM2 (0.46) | — | |
| SCHEMBL11066226 | 0.89 | DRD4 (0.62) | — | |
| SCHEMBL11064740 | 0.88 | PRMT5 (0.47) | KCNH2 | |
| SCHEMBL11072463 | 0.88 | DRD2 (0.46) | KCNH2 | |
| SCHEMBL11071842 | 0.87 | SLC18A3 (0.48) | KCNH2 | |
| SCHEMBL10578077 | 0.85 | HTR7 (0.63) | — | |
| SCHEMBL11071029 | 0.84 | CHRM2 (0.59) | — | |
| SCHEMBL11070374 | 0.83 | CHRM1 (0.52) | KCNH2 | |
| SCHEMBL11061136 | 0.82 | KCNH2 (0.56) | KCNH2 | |
| SCHEMBL11068167 | 0.80 | TSHR (0.47) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4482560-A | Carbostyril derivatives, and antihistaminic agents containing the same | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1984-11-13 | — | — | US | disclosed |