Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX2 | P34913 | 4/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.43 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.43 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.43 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 2/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.42 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.41 |
| ▸ | PIN1 | Q13526 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | BLM | P54132 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | HTR2C | P28335 | 1/20 | 0.40 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.40 |
| ▸ | KEAP1 | Q14145 | 2/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2067933 | 0.84 | PYGL (0.42) | TSHRNPSR1MEN1KMT2A | |
| SCHEMBL8702315 | 0.80 | KDM1A (0.44) | EPHX2FFAR1 | |
| SCHEMBL9266532 | 0.79 | CYP1A2 (0.46) | EPHX2CYP1A2CYP2D6CYP2C9CYP2C19 | |
| SCHEMBL13453149 | 0.77 | LMNA (0.43) | EPHX2CYP1A2CYP2D6CYP2C9CYP2C19 | |
| Succinic Acid SCHEMBL139964 | 0.77 | HTR2C (0.45) | EPHX2CYP1A2CYP2D6CYP2C9CYP2C19 | |
| SCHEMBL7845908 | 0.77 | FFAR1 (0.62) | FFAR1 | |
| SCHEMBL7901109 | 0.77 | CYP1A2 (0.47) | EPHX2CYP1A2CYP2D6CYP2C9CYP2C19 | |
| SCHEMBL7847075 | 0.77 | FFAR1 (0.62) | FFAR1 | |
| SCHEMBL1470461 | 0.77 | FFAR1 (0.62) | FFAR1 | |
| SCHEMBL14226877 | 0.77 | CYP1A2 (0.47) | EPHX2CYP1A2CYP2D6CYP2C9CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4471124-A | DIABETIC COMPLICATIONS | PFIZER INC. (US) | 1984-09-11 | — | — | US | disclosed |
| US-4442114-A | COMPLICATIONS OF DIABETES | PFIZER INC. (US) | 1984-04-10 | — | — | US | disclosed |
| US-4307108-A | DIABETES | PFIZER INC. (US) | 1981-12-22 | — | — | US | disclosed |