Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX5 | P09917 | 7/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.44 |
| ▸ | MEN1 | O00255 | 3/20 | 0.44 |
| ▸ | LMNA | P02545 | 3/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 2/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.44 |
| ▸ | PTGES | O14684 | 2/20 | 0.41 |
| ▸ | MAOB | P27338 | 2/20 | 0.41 |
| ▸ | PDE3B | Q13370 | 1/20 | 0.40 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
| ▸ | GABRA2 | P47869 | 1/20 | 0.38 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11059882 | 0.92 | ALOX5 (0.46) | ALOX5SMN1; SMN2KMT2AMEN1LMNA | |
| SCHEMBL11063907 | 0.89 | ALOX5 (0.43) | ALOX5SMN1; SMN2KMT2AMEN1LMNA | |
| SCHEMBL11069392 | 0.89 | SMN1; SMN2 (0.51) | ALOX5SMN1; SMN2KMT2AMEN1LMNA | |
| SCHEMBL11065605 | 0.88 | MAOB (0.41) | ALOX5SMN1; SMN2KMT2AMEN1LMNA | |
| SCHEMBL11068597 | 0.82 | ALOX5 (0.47) | ALOX5SMN1; SMN2KMT2AMEN1LMNA | |
| SCHEMBL11064362 | 0.79 | MAPT (0.48) | ALOX5SMN1; SMN2KMT2AMEN1LMNA | |
| SCHEMBL11191094 | 0.78 | ALDH1A1 (0.45) | SMN1; SMN2KMT2AMEN1LMNAALDH1A1 | |
| SCHEMBL11071958 | 0.77 | ALOX5 (0.53) | ALOX5SMN1; SMN2KMT2AMEN1LMNA | |
| SCHEMBL11198914 | 0.76 | ALOX5 (0.56) | ALOX5SMN1; SMN2KMT2AMEN1LMNA | |
| SCHEMBL11063059 | 0.74 | ALOX5 (0.44) | ALOX5SMN1; SMN2KMT2AMEN1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4444981-A | ANTIINFLAMMATORY, ANALGESICS | BEECHAM GROUP LIMITED (GB) | 1984-04-24 | — | — | US | disclosed |
| EP-0024807-B1 | BENZOCYCLOHEPTAPYRROLEALKANOIC ACIDS AND THEIR DERIVATIVES, PROCESSES FOR THEIR PREPARATION AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | BEECHAM GROUP PLC (GB) | 1983-11-02 | — | — | EP | disclosed |
| EP-0024807-A1 | Benzocycloheptapyrrolealkanoic acids and their derivatives, processes for their preparation and pharmaceutical compositions containing them | BEECHAM GROUP PLC (GB) | 1981-03-11 | — | — | EP | disclosed |