Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOA | P21397 | 11/20 | 0.61 |
| ▸ | MAOB | P27338 | 11/20 | 0.61 |
| ▸ | DRD2 | P14416 | 8/20 | 0.58 |
| ▸ | DRD3 | P35462 | 7/20 | 0.58 |
| ▸ | DRD4 | P21917 | 6/20 | 0.58 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11064706 | 0.93 | DRD2 (0.56) | MAOAMAOBDRD2DRD3DRD4 | |
| SCHEMBL11064821 | 0.91 | MAOA (0.65) | MAOAMAOBDRD2DRD3DRD4 | |
| SCHEMBL11062767 | 0.89 | MAOA (0.66) | MAOAMAOBDRD2DRD3DRD4 | |
| SCHEMBL11066559 | 0.84 | DRD2 (0.59) | MAOAMAOBDRD2DRD3DRD4 | |
| SCHEMBL11062925 | 0.83 | DRD2 (0.75) | MAOAMAOBDRD2DRD3DRD4 | |
| SCHEMBL11068976 | 0.82 | S1PR5 (0.47) | DRD2DRD3DRD4 | |
| SCHEMBL11070110 | 0.82 | S1PR5 (0.47) | DRD2DRD3DRD4 | |
| SCHEMBL11070987 | 0.81 | DRD2 (0.60) | MAOAMAOBDRD2DRD3DRD4 | |
| SCHEMBL10571208 | 0.81 | MAOA (0.79) | MAOAMAOBDRD2DRD3DRD4 | |
| SCHEMBL11063037 | 0.79 | DRD2 (0.79) | MAOAMAOBDRD2DRD3DRD4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4482560-A | Carbostyril derivatives, and antihistaminic agents containing the same | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1984-11-13 | — | — | US | disclosed |