Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | ENPP2 | Q13822 | 1/20 | 0.38 |
| ▸ | DRD2 | P14416 | 1/20 | 0.37 |
| ▸ | DRD4 | P21917 | 1/20 | 0.37 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.37 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.37 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.37 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.37 |
| ▸ | HTR1A | P08908 | 1/20 | 0.37 |
| ▸ | FPR2 | P25090 | 1/20 | 0.37 |
| ▸ | PROKR1 | Q8TCW9 | 1/20 | 0.37 |
| ▸ | HTR2C | P28335 | 1/20 | 0.37 |
| ▸ | HTR7 | P34969 | 1/20 | 0.37 |
| ▸ | HTR2B | P41595 | 1/20 | 0.37 |
| ▸ | HTR3A | P46098 | 1/20 | 0.37 |
| ▸ | HTR4 | Q13639 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL11065793 | 0.99 | HRH3 (0.44) | HRH3KDM4ESMN1; SMN2ENPP2DRD2 | |
| SCHEMBL6926846 | 0.77 | L3MBTL1 (0.47) | HRH3KDM4E | |
| SCHEMBL11065075 | 0.76 | SLC6A4 (0.49) | SLC6A2SLC6A3SLC6A4HTR1A | |
| SCHEMBL10058617 | 0.75 | PDE3B (0.48) | HRH3DRD2DRD4SLC6A4 | |
| SCHEMBL11069093 | 0.75 | SLC6A2 (0.63) | SLC6A2SLC6A3SLC6A4CHRM3HTR1A | |
| Hydrochloric Acid SCHEMBL11068846 | 0.74 | SLC6A2 (0.61) | SLC6A2SLC6A3SLC6A4CHRM3HTR1A | |
| SCHEMBL11068301 | 0.73 | MEN1 (0.54) | HRH3DRD2HTR1AHTR2C | |
| SCHEMBL12126004 | 0.72 | SCD (0.46) | HRH3KDM4EHTR2CHTR2B | |
| Hydrochloric Acid SCHEMBL10964879 | 0.72 | HRH3 (0.66) | HRH3SMN1; SMN2HTR7 | |
| SCHEMBL20176375 | 0.71 | SLC6A4 (0.55) | KDM4EDRD4SLC6A2SLC6A3SLC6A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4443462-A | Antipsychotic 4-(naphthalenyloxy)piperidine derivatives | MERRELL DOW PHARMACEUTICALS INC. (US) | 1984-04-17 | — | — | US | disclosed |