Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A4 | P31645 | 6/20 | 0.49 |
| ▸ | SLC6A3 | Q01959 | 6/20 | 0.49 |
| ▸ | HTR1A | P08908 | 2/20 | 0.49 |
| ▸ | SLC6A2 | P23975 | 3/20 | 0.48 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.45 |
| ▸ | GRIN2D | O15399 | 1/20 | 0.45 |
| ▸ | GRIN3B | O60391 | 1/20 | 0.45 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.45 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.45 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.45 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.45 |
| ▸ | GRIN2A | Q12879 | 1/20 | 0.45 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.45 |
| ▸ | GRIN2C | Q14957 | 1/20 | 0.45 |
| ▸ | GRIN3A | Q8TCU5 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11065888 | 0.80 | DRD2 (0.48) | SLC6A4SLC6A3SIGMAR1 | |
| SCHEMBL19852044 | 0.79 | CARM1 (0.57) | SLC6A4SLC6A3HTR1ASLC6A2GRIN2D | |
| SCHEMBL19852050 | 0.79 | CARM1 (0.57) | SLC6A4SLC6A3HTR1ASLC6A2GRIN2D | |
| SCHEMBL21071819 | 0.79 | CARM1 (0.57) | SLC6A4SLC6A3HTR1ASLC6A2GRIN2D | |
| SCHEMBL11065058 | 0.76 | HRH3 (0.45) | SLC6A4SLC6A3HTR1ASLC6A2 | |
| Hydrochloric Acid SCHEMBL11065793 | 0.75 | HRH3 (0.44) | SLC6A4SLC6A3SLC6A2 | |
| SCHEMBL11072827 | 0.74 | SIGMAR1 (0.45) | SIGMAR1 | |
| SCHEMBL11066510 | 0.72 | HTR2A (0.42) | HTR1ASIGMAR1 | |
| SCHEMBL11065708 | 0.72 | HTR5A (0.46) | SIGMAR1 | |
| SCHEMBL11068301 | 0.71 | MEN1 (0.54) | HTR1AADRA1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4443462-A | Antipsychotic 4-(naphthalenyloxy)piperidine derivatives | MERRELL DOW PHARMACEUTICALS INC. (US) | 1984-04-17 | — | — | US | disclosed |