Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE3B | Q13370 | 11/20 | 0.33 |
| ▸ | PDE3A | Q14432 | 11/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.32 |
| ▸ | PDE2A | O00408 | 2/20 | 0.30 |
| ▸ | P2RY12 | Q9H244 | 2/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11064332 | 0.92 | PDE3B (0.38) | PDE3BPDE3AALDH1A1PDE2AP2RY12 | |
| SCHEMBL11062550 | 0.89 | PDE3B (0.40) | PDE3BPDE3APDE2AP2RY12 | |
| SCHEMBL11067577 | 0.82 | PDE3B (0.38) | PDE3BPDE3AALDH1A1P2RY12 | |
| SCHEMBL11071569 | 0.81 | PDE3B (0.47) | PDE3BPDE3AALDH1A1PDE2AP2RY12 | |
| SCHEMBL11064304 | 0.79 | PDE3B (0.46) | PDE3BPDE3AALDH1A1PDE2AP2RY12 | |
| SCHEMBL11067558 | 0.77 | KMT2A (0.36) | PDE3BPDE3AALDH1A1 | |
| SCHEMBL11065345 | 0.76 | PDE3B (0.60) | PDE3BPDE3AALDH1A1 | |
| SCHEMBL11064753 | 0.72 | PDE3B (0.50) | PDE3BPDE3APDE2AP2RY12 | |
| SCHEMBL11058595 | 0.72 | PDE3B (0.35) | PDE3BPDE3AALDH1A1 | |
| SCHEMBL11064228 | 0.71 | ALDH1A1 (0.40) | PDE3BPDE3AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4435404-A | ANTICOAGULANTS | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1984-03-06 | — | — | US | disclosed |