Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA12 | O43570 | 6/20 | 0.42 |
| ▸ | CA9 | Q16790 | 6/20 | 0.42 |
| ▸ | CA2 | P00918 | 5/20 | 0.42 |
| ▸ | PTGS2 | P35354 | 3/20 | 0.40 |
| ▸ | PTGES | O14684 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | USP2 | O75604 | 1/20 | 0.39 |
| ▸ | CA1 | P00915 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | BCHE | P06276 | 1/20 | 0.39 |
| ▸ | CA4 | P22748 | 1/20 | 0.39 |
| ▸ | CA6 | P23280 | 1/20 | 0.39 |
| ▸ | CA5A | P35218 | 1/20 | 0.39 |
| ▸ | CA7 | P43166 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.39 |
| ▸ | CA5B | Q9Y2D0 | 1/20 | 0.39 |
| ▸ | MMP3 | P08254 | 1/20 | 0.39 |
| ▸ | BCL2L1 | Q07817 | 1/20 | 0.39 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2004460 | 0.96 | CA12 (0.43) | CA12CA9CA2PTGS2PTGES | |
| SCHEMBL11066725 | 0.84 | NTRK3 (0.41) | CA12CA9CA2PTGS2PTGES | |
| SCHEMBL11060876 | 0.84 | PTGES (0.39) | CA12CA9CA2PTGS2PTGES | |
| SCHEMBL11062987 | 0.82 | RET (0.42) | CA12CA9CA2PTGS2PTGES | |
| SCHEMBL11065993 | 0.82 | CA12 (0.38) | CA12CA9CA2PTGS2PTGES | |
| SCHEMBL1997613 | 0.75 | MEN1 (0.43) | CA12CA9PTGS2PTGESKDM4E | |
| SCHEMBL3487322 | 0.74 | CA12 (0.43) | CA12CA9CA2KDM4EUSP2 | |
| SCHEMBL28739981 | 0.74 | CA12 (0.43) | CA12CA9CA2PTGS2KDM4E | |
| SCHEMBL11659237 | 0.69 | P2RX7 (0.43) | CA12CA9CA2CA1LMNA | |
| SCHEMBL11270084 | 0.68 | PTGS2 (0.61) | PTGS2MMP3BCL2L1MAOAMAOB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4428956-A | GLYCOLATE OXIDASE INHIBITORS | MERCK & CO., INC. (US) | 1984-01-31 | — | — | US | disclosed |