Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.44 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.42 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 3/20 | 0.37 |
| ▸ | MGAM | O43451 | 1/20 | 0.37 |
| ▸ | SI | P14410 | 1/20 | 0.37 |
| ▸ | MGAM2 | Q2M2H8 | 1/20 | 0.37 |
| ▸ | SOAT1 | P35610 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 2/20 | 0.36 |
| ▸ | CAD | P27708 | 1/20 | 0.35 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.34 |
| ▸ | GLO1 | Q04760 | 1/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
| ▸ | CPB2 | Q96IY4 | 1/20 | 0.34 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1340978 | 0.95 | ALDH1A1 (0.48) | ALDH1A1LMNAHSD17B10ALOX15CYP2D6 | |
| Hydrochloric Acid SCHEMBL1340977 | 0.93 | ALDH1A1 (0.46) | ALDH1A1LMNAHSD17B10ALOX15CYP2D6 | |
| Hydrochloric Acid SCHEMBL9082110 | 0.93 | ALDH1A1 (0.46) | ALDH1A1LMNAHSD17B10ALOX15CYP2D6 | |
| SCHEMBL338079 | 0.83 | ALOX15 (0.52) | ALDH1A1LMNAHSD17B10ALOX15CYP2D6 | |
| Acetic Acid SCHEMBL28002636 | 0.81 | ALDH1A1 (0.48) | ALDH1A1LMNAHSD17B10ALOX15CYP2D6 | |
| Hydrochloric Acid SCHEMBL275716 | 0.80 | ALOX15 (0.50) | ALDH1A1LMNAHSD17B10ALOX15CYP2D6 | |
| SCHEMBL28219320 | 0.77 | ALDH1A1 (0.38) | ALDH1A1LMNAHSD17B10ALOX15TSHR | |
| SCHEMBL4405650 | 0.76 | ALOX15 (0.46) | ALDH1A1LMNAHSD17B10ALOX15CYP2D6 | |
| SCHEMBL15083214 | 0.76 | ALOX15 (0.46) | ALDH1A1LMNAHSD17B10ALOX15CYP2D6 | |
| SCHEMBL12582818 | 0.76 | ALOX15 (0.46) | ALDH1A1LMNAHSD17B10ALOX15CYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4444771-A | Azeto triazolo pyrazine β-lactam antibacterial agents | BEECHAM GROUP LIMITED (GB) | 1984-04-24 | — | — | US | disclosed |
| EP-0048096-A1 | Beta-lactam antibacterial agents | BEECHAM GROUP PLC (GB) | 1982-03-24 | — | — | EP | disclosed |