Sugi Predict

Sugi Predict / Compounds / SCHEMBL338079

SCHEMBL338079

SCHEMBL338079

CCOC(=O)C(N)C(=O)OCC

nearest known ligand 0.52

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ ALOX15 P16050 1/20 0.52
▸ ALDH1A1 P00352 5/20 0.50
▸ LMNA P02545 1/20 0.48
▸ HSD17B10 Q99714 1/20 0.48
▸ GAA P10253 2/20 0.46
▸ MGAM O43451 1/20 0.46
▸ SI P14410 1/20 0.46
▸ MGAM2 Q2M2H8 1/20 0.46
▸ SOAT1 P35610 1/20 0.46
▸ CYP2D6 P10635 1/20 0.42
▸ CYP2C9 P11712 1/20 0.42
▸ CYP2C19 P33261 1/20 0.42
▸ TRPA1 O75762 1/20 0.42
▸ CYP1A2 P05177 1/20 0.41
▸ CAD P27708 1/20 0.41
▸ CPB2 Q96IY4 1/20 0.39
▸ POLB P06746 1/20 0.39
▸ HPGD P15428 2/20 0.38
▸ MAPT P10636 1/20 0.38
▸ SMN1; SMN2 Q16637 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Hydrochloric Acid SCHEMBL275716 0.97 ALOX15 (0.50) ALOX15ALDH1A1LMNAHSD17B10GAA
Acetic Acid SCHEMBL28002636 0.92 ALDH1A1 (0.48) ALOX15ALDH1A1LMNAHSD17B10GAA
SCHEMBL24016832 0.90 GAA (0.44) ALOX15ALDH1A1LMNAHSD17B10GAA
SCHEMBL4405650 0.87 ALOX15 (0.46) ALOX15ALDH1A1LMNAHSD17B10GAA
SCHEMBL12582818 0.87 ALOX15 (0.46) ALOX15ALDH1A1LMNAHSD17B10GAA
SCHEMBL15083214 0.87 ALOX15 (0.46) ALOX15ALDH1A1LMNAHSD17B10GAA
SCHEMBL1340978 0.87 ALDH1A1 (0.48) ALOX15ALDH1A1LMNAHSD17B10GAA
Malonic Acid SCHEMBL18956012 0.86 ALOX15 (0.41) ALOX15ALDH1A1LMNAHSD17B10GAA
Hydrochloric Acid SCHEMBL1437174 0.85 ALOX15 (0.44) ALOX15ALDH1A1LMNAHSD17B10GAA
SCHEMBL8897912 0.85 ALOX15 (0.44) ALOX15ALDH1A1LMNAHSD17B10GAA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 694 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-118702636-A Method for preparing 5-hydroxy-1- (4-methoxyphenyl) -1,2, 3-triazole-4-carboxylic acid ethyl ester through continuous flow 深圳智微通科技有限公司 2024-09-27 — — CN claimed
CN-118239879-A Method for preparing 3-substituted oxindole, dihydroisoindigo and tetra-substituted ethane based on primary amine and application of primary amine 泰山学院 2024-06-25 — — CN claimed
CN-117861715-A Aromatic-enriched refined heavy distillate hydrocracking catalyst, preparation method thereof and aromatic-enriched heavy distillate hydrocracking method 中国石油化工股份有限公司 2024-04-12 — — CN claimed
CN-115974790-A Method for synthesizing ticagrelor six-membered ring intermediate 赣州康瑞泰药业有限公司 2023-04-18 — — CN claimed
CN-115073478-B Indole 3,4-diazepine Zhuo Huanhua compound, and preparation method and application thereof 青岛农业大学 2023-04-07 — — CN claimed
CN-115090422-A Amino acid type collecting agent and preparation method and application thereof 山东理工大学 2022-09-23 — — CN claimed
CN-112661913-B Preparation method of functional polycarboxylic acid water reducer capable of resisting flocculating agent in machine-made sand 江苏亚琛材料科技有限公司 2022-09-20 — — CN claimed
CN-115073478-A Indole 3, 4-position azatrane compound, preparation method and application thereof 青岛农业大学 2022-09-20 — — CN claimed
CN-112267304-B Preparation method of ultraviolet-proof shirt fabric 浙江金澜服饰股份有限公司 2022-07-22 — — CN claimed
CN-114685301-A Production improvement method of 2-amino malonamide 山东省药学科学院 2022-07-01 — — CN claimed
CN-105295353-A Binder for casting and preparation method thereof SUZHOU JIEDERUI PREC MACHINERY CO LTD 2016-02-03 — — CN claimed
CN-105218425-A A kind of synthetic method of 3,5-dimethoxy pyrroles-2-formic acid DING YUQIN 2016-01-06 — — CN claimed
US-8664405-B2 Sulfonic acid salt compound of 4-carbamoyl-5-hydroxy-imidazole derivative FUJIFILM CORPORATION (JP) 2014-03-04 — — US claimed
CN-102351769-A Chiral 2,5-pyrroline derivative, and synthetic method and biological activity thereof USTC UNIV SCIENCE TECH CN 2012-02-15 — — CN claimed
US-20100210855-A1 SULFONIC ACID SALT COMPOUND OF 4-CARBAMOYL-5-HYDROXY-IMIDAZOLE DERIVATIVE FUJIFILM CORPORATION (JP) 2010-08-19 — — US claimed
EP-2196460-A1 SULFONIC ACID SALT COMPOUND OF 4-CARBAMOYL-5-HYDROXY-IMIDAZOLE DERIVATIVE MBR Co., Ltd. (JP) 2010-06-16 — — EP claimed
US-20040067531-A1 Methods of modulating protein tyrosine kinase function with substituted indolinone compounds SUGEN, INC. 2004-04-08 — — US claimed
EP-0612211-B1 ALTERATION OF RATE AND CHARACTER OF HAIR GROWTH GILLETTE CO (US) 2002-06-05 — — EP claimed
US-5444090-A Applying a synthetase inhibitor GILLETTE COMPANY, THE, (A DELAWARE CORPORATION) 1995-08-22 — — US claimed
WO-1993008687-A1 ALTERATION OF RATE AND CHARACTER OF HAIR GROWTH HANDELMAN JOSEPH H (US) 1993-05-13 — — WO claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20040067531-A1 Methods of modulating protein tyrosine kinase function with substituted indolinone compounds ABL1, LCK, PNCK ALOX15 4484/4885ALDH1A1 3893/4885LMNA 4040/4885
US-20100210855-A1 SULFONIC ACID SALT COMPOUND OF 4-CARBAMOYL-5-HYDROXY-IMIDAZOLE DERIVATIVE CA12, CA14, CA2 ALOX15 3890/4885ALDH1A1 2965/4885LMNA 4541/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.