Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 1/20 | 0.60 |
| ▸ | DRD4 | P21917 | 6/20 | 0.58 |
| ▸ | ABCB1 | P08183 | 4/20 | 0.51 |
| ▸ | POLB | P06746 | 1/20 | 0.51 |
| ▸ | TSHR | P16473 | 1/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.50 |
| ▸ | MEN1 | O00255 | 2/20 | 0.50 |
| ▸ | DRD2 | P14416 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 1/20 | 0.47 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.47 |
| ▸ | ATM | Q13315 | 1/20 | 0.47 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.46 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.46 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11069003 | 0.83 | DRD4 (0.62) | GAADRD4ABCB1POLBTSHR | |
| SCHEMBL11073897 | 0.77 | ABCB1 (0.62) | GAADRD4ABCB1KMT2AMEN1 | |
| SCHEMBL11066226 | 0.76 | DRD4 (0.62) | GAADRD4POLBTSHRKMT2A | |
| SCHEMBL11073834 | 0.75 | SLC6A2 (0.56) | — | |
| SCHEMBL12577241 | 0.75 | DRD4 (0.84) | GAADRD4ABCB1POLBTSHR | |
| Oxalic Acid SCHEMBL11060455 | 0.75 | ABCB1 (0.61) | GAADRD4ABCB1KMT2AMEN1 | |
| SCHEMBL11071842 | 0.74 | SLC18A3 (0.48) | GAADRD4KMT2AMEN1DRD2 | |
| SCHEMBL7999064 | 0.74 | DRD4 (0.86) | GAADRD4ABCB1POLBTSHR | |
| SCHEMBL11062784 | 0.73 | ABCB1 (0.60) | GAADRD4ABCB1KMT2AMEN1 | |
| SCHEMBL11065731 | 0.73 | DRD4 (0.58) | GAADRD4ABCB1POLBTSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4482560-A | Carbostyril derivatives, and antihistaminic agents containing the same | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1984-11-13 | — | — | US | disclosed |