Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD4 | P21917 | 6/20 | 0.62 |
| ▸ | GAA | P10253 | 1/20 | 0.61 |
| ▸ | ABCB1 | P08183 | 4/20 | 0.54 |
| ▸ | POLB | P06746 | 1/20 | 0.54 |
| ▸ | TSHR | P16473 | 1/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.53 |
| ▸ | MEN1 | O00255 | 2/20 | 0.53 |
| ▸ | DRD2 | P14416 | 1/20 | 0.51 |
| ▸ | ATM | Q13315 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11066226 | 0.89 | DRD4 (0.62) | DRD4GAAPOLBTSHRKMT2A | |
| SCHEMBL11071842 | 0.87 | SLC18A3 (0.48) | DRD4GAAKMT2AMEN1DRD2 | |
| SCHEMBL11065731 | 0.86 | DRD4 (0.58) | DRD4GAAABCB1POLBTSHR | |
| SCHEMBL11063923 | 0.85 | KMT2A (0.61) | DRD4GAAABCB1KMT2AMEN1 | |
| SCHEMBL11065263 | 0.85 | CHRNA7 (0.48) | DRD4GAAKMT2AMEN1DRD2 | |
| SCHEMBL11070228 | 0.84 | MAOB (0.62) | DRD4DRD2 | |
| SCHEMBL10571746 | 0.83 | HTR7 (0.66) | POLBKMT2A | |
| Oxalic Acid SCHEMBL11064085 | 0.83 | MAOB (0.60) | DRD4KMT2AMEN1DRD2 | |
| SCHEMBL11065355 | 0.83 | GAA (0.60) | DRD4GAAABCB1POLBTSHR | |
| SCHEMBL11065197 | 0.81 | DRD4 (0.52) | DRD4DRD2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4482560-A | Carbostyril derivatives, and antihistaminic agents containing the same | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1984-11-13 | — | — | US | disclosed |